Why is Hydralazine prescribed?

Hydralazine is prescribed for the treatment of hypertension that may cause myocardial infarction, stroke, kidney problems and other heart problems.

What does it do?

Hydralazine, a potent vasodilator, is an anti-hypertensive agent that primarily works by altering the calcium synthesis in the vascular smooth muscle which is responsible for contraction state; thus, helping the blood flow smoothly through relaxation of the blood vessels.

How should I take it?

Hydralazine is available as 50mg tablet that is intended for oral administration as a whole, not to be crushed or chewed, and should be taken once daily with or without food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

Always consult your doctor about any concerns you may have when taking Hydralazine.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Hydralazine?

Before taking Hydralazine, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had coronary artery disease, rheumatic heart disease, stroke, kidney problems and myocardial infarction.

Avoid drinking alcohol as this may cause dizziness and drowsiness and can add to the effects of Hydralazine.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Hydralazine, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Anorexia
• Chest pain
• Diarrhea
• Headache
• Loss of appetite
• Nausea
• Palpitations
• Tachycardia
• Vomiting

Serious side effects may include:
• Agranulocytosis
• Hepatitis
• Leukopenia
• Paralytic ileus
• Peripheral neuritis
• Pruritus
• Purpura
• Systemic lupus erythematosus syndrome
• Thrombocytopenia
• Urticaria
• Vascular collapse

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Hydralazine with any of the following medications:

• Acebutolol
• Alphagan
• Aspilet
• Auvi-Q
• Avanafil
• Azilect
• Betaxolol
• Carbidopa
• Carvid
• Cataflam
• Celebrex
• Combigan
• Concore
• Dobutamine
• Dopamine
• Feldene
• Indocin
• Isocarboxacid
• Levodopa
• Lofexidine
• Lopressor
• Mobic
• Nebilet
• Normodyne
• Parecoxib
• Pindolol
• Ponstan
• Pretomanid
• Skelan
• Tenormin
• Voltaren
• Yohimbine
• Zyvox

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Hydralazine at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant from the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Hydralazine to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.

The presence of Hydralazine in human milk is still unknown. Consult your doctor before breastfeeding.

The use of Hydralazine in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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