NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Marcaine Injection prescribed?

Marcaine (Bupivacaine hydrochloride) Injection is a numbing medication used as a local anesthetic for spinal block procedures.

What does it do?

Bupivacaine helps prevent pain during certain procedures by blocking sensation in the skin or surrounding tissues.

How should I take it?

This medication is administered by injection directly into the affected area. A healthcare provider will give it in a hospital or clinic setting.

What if I missed a dose?

This medication is not intended for regular use.

What are the special precautions before taking Marcaine Injection?

Inform your doctor about all the medications you are taking, your current and previous medical history.

• Liver disease
• Low blood pressure
• G6PD deficiency
• Heart disease
• Kidney disease
• Lung or breathing problems (such as asthma or COPD)
• If you are breastfeeding
• If you are pregnant or trying to become pregnant

Your health will be closely monitored while you are using this medication.

Take care to avoid injury in the numb area, as you may not feel pain.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

• Seizures
• Allergic reactions such as hives, rash, swelling of the face or throat
• Heart rhythm changes such as fast or irregular heartbeat or trouble breathing
• Central nervous system (CNS) depression such as slow or shallow breathing, shortness of breath, or difficulty staying awake
• Methemoglobinemia such as difficulty breathing, rapid or irregular heartbeat, extreme fatigue or weakness

Less serious side effects that usually do not need medical attention (but report them if they persist):

• Anxiety or nervousness
• Nausea
• Drowsiness
• Vomiting

This may not be a complete list of side effects. For medical advice about side effects, contact your doctor.

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Marcaine Injection with any of the following medications:

• Acetaminophen
• Nitric oxide
• Nitroglycerin
• Nitroprusside
• Flutamide
• Hydroxyurea
• Ifosfamide
• Chloroquine
• Cyclophosphamide
• Metoclopramide
• Nitrous oxide
• Local anesthetics like Lidocaine, Tetracaine
• Primaquine
• Quinine
• Rasburicase
• Sulfasalazine
• Certain antibiotics such as Dapsone, Nitrofurantoin
• Some seizure medications, including Phenobarbital, Phenytoin

This list may not include all possible interactions. Be sure to provide your doctor with a complete list of all medications.

How should I store it?

This medication is administered in a hospital or clinic and is not intended to be stored or used at home.

What action should I take in case of overdose?

If you suspect that you have received too much Marcaine Injection, seek immediate help or going to the nearest emergency room.

Is it safe for pregnant or breastfeeding women?

During pregnancy, Marcaine should be used only when prescribed by a doctor, as it may pose risks to the fetus. This medication can also pass into breast milk and potentially harm a nursing baby. Be sure to consult your doctor before breastfeeding.

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