NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Zonalon prescribed?

Zonalon (Topical use) is prescribed to relieve itching in adults with eczema or other skin conditions that cause frequent scratching and thickening of the skin.

What does it do?

Zonalon works by inhibiting histamine, a chemical released by the body during allergic reactions.

How should I take it?

Zonalon is intended for external use only. Apply a thin layer of Zonalon to the affected area as prescribed. Do not cover the treated area with a bandage or dressing. Avoid contact with your eyes; if the medication gets into your eyes, rinse thoroughly with plenty of cool tap water.

What if I missed a dose?

Apply the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed one. Do not take extra medicine to compensate for the missed dose.

What are the special precautions before taking Zonalon?

Inform your doctor about all the medications you are taking, your current and previous medical history.

Make sure to inform your doctor if you have any of the following conditions:

• Liver disease
• Prostate problems
• Schizophrenia
• Seizure disorders
• Bipolar disorder
• Difficulty urinating
• Glaucoma
• Heart disease
• Regular consumption of alcoholic beverages
• Lung or breathing disorders, such as asthma or sleep apnea

Zonalon is not approved for use in individuals under 18 years of age.

Does it have any side effects?

While the risk of serious side effects from applying Zonalon to the skin is low, side effects can occur if the medication is absorbed into your bloodstream. You may experience drowsiness after using this medicine, especially when applied to large areas of skin.

Zonalon may cause serious side effects. Discontinue use and contact your doctor immediately if you experience:

Serious side effects may include:
• Confusion
• Blurred vision
• Severe dry mouth
• Severe drowsiness
• Painful or difficult urination
• New or worsening skin symptoms

Older adults may be at a higher risk for some side effects.

Common side effects may include:
• Dry mouth
• Mild drowsiness
• Burning or stinging at the application site

This is not a complete list of side effects. Contact your doctor for medical advice if you experience any side effects.

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Zonalon with any of the following medications:

• Alcohol
• Cimetidine
• Linezolid
• Methylene blue
• Dextromethorphan (found in some cough medicines)
• Medications used to correct heart rhythm disorders
• Antidepressants, especially MAO inhibitors like Parnate
• Any drugs that cause drowsiness or aid sleep, such as tranquilizers, antihistamines, muscle relaxants, and others

This list may not include all potential interactions. Be sure to provide your doctor with a complete list of all medications.

How should I store it?

Store at room temperature, away from moisture and heat. Keep the tube securely closed when not in use.

What action should I take in case of overdose?

If you suspect an overdose of Zonalon, contact your provider or go to the emergency room immediately as it can cause death.

Is it safe for pregnant or breastfeeding women?

Pregnancy: It is unclear whether topical Doxepin can affect pregnancy or harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant.

Breastfeeding: Topical Doxepin may be passed through breast milk. Notify your doctor if you are breastfeeding or intend to breastfeed. They will advise you whether to discontinue breastfeeding or stop using topical Doxepin.

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