Why is Aceon prescribed?

Perindopril (Aceon) is prescribed for the treatment of hypertension (high blood pressure) and to prevent the occurrence of heart attacks in people with coronary heart disease. It can be used alone or with other drugs.

What does it do?

Hypertension is a medical condition wherein the force that the blood exerts on the walls of your blood vessels is too high. Untreated hypertension can lead to problems such as heart diseases, heart attacks, stroke, and kidney problems.

In coronary heart disease, the coronary arteries become narrow or blocked due to the build up of plaque (cholesterol and fat deposits) and other causes. This may reduce the amount of blood flowing into the heart and cause symptoms such as chest pain and in serious cases, a heart attack.

Perindopril is classified as an angiotensin-converting enzyme inhibitor and it inhibits the release of substances that tighten the blood vessels and it also prevents water retention which causes high blood pressure.

How should I take it?

Aceon is available in 2mg, 4mg, and 8mg tablets intended for oral administration every day with or without meals. Swallow the tablet as a whole and do not crush, chew, break it in half, or tamper the tablet in any way. Increase your water intake when taking Aceon.

Take Aceon exactly as your doctor instructed and do not make alterations in the dosage or frequency. Your doctor will make adjustments to your dosage as necessary.

Aceon does not treat your condition, it only controls it. Always consult your doctor before stopping the medication and clarify any concerns you may have when taking Aceon.

You should incorporate a healthy diet and regular exercise in your lifestyle. This is beneficial in controlling your blood pressure.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before using Aceon?

Inform your doctor if you are allergic to Perindopril, other medications that belong in the same category such as Benazepril, Captopril, Enalapril, Fosinopril, Lisinopril, Moexipril, Quinapril, Ramipril, Trandolapril, any component of Aceon, and other medications.

Inform your doctor if you are taking Valsartan and Sacubitril, or have stopped taking it within the last 36 hours. Also, inform your doctor if you have diabetes and are taking a medication called Aliskiren. Taking Perindopril may not be suitable for you in these cases and should be discussed with your doctor.

Tell your doctor if you have kidney disease and are on dialysis, liver disease, heart disease, lupus, scleroderma, or angioedema.

For the drug label information of Aceon, click here.

Does it have any side effects?

Most drugs have the possibility of exhibiting side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Back pain
• Cough
• Diarrhea
• Dizziness
• Fatigue
• Headache
• Stomach pain

Serious side effects include:
• Chest pain
• Fainting
• Fever
• Irregular heartbeats
• Lightheadedness
• Numbness in the hands or feet
• Sore throat
• Swelling of the face, tongue, lips, eyes, and extremities

Other side effects not listed above may be experienced when taking Aceon. If the symptoms do not go away or are life-threatening, immediately inform your doctor or call an ambulance for professional medical assistance.

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Aceon with any of the following medications:

• Aldactone
• Amiloride
• Amphotericin B
• Arava
• Atacand
• Avapro
• Azilsartan medoxomil
• Benicar
• Betaxolol
• Cordarone
• Cosopt
• Cozaar
• Diovan
• Dopamine
• Doxofylline
• Dyrenium
• Heparin
• Hydralazine
• Ibuprofen
• Ifosfamide
• Indocin
• Isordil
• K-dur
• Lasix
• Lithium
• Lomitapide
• Loperamide
• Metaglip
• Micardis
• Milrinone
• Mipomersen
• Mobic
• Nitrofurantoin
• Nitrolingual
• Norepinephrine
• Pexidartinib
• Procainamide
• Restasis
• Sinemet Plus
• Tekturna
• Teriflunomide
• Trimethoprim
• Viagra
• Xatral
• Xeloda
• Zanaflex
• Zebeta
• Zyloprim

Interaction with herbs:

• Bayberry
• Blue cohosh
• Cayenne
• Ephedra
• Licorice


Avoid eating food that contains high amounts of potassium and do not use salt substitutes or potassium supplements when taking Perindopril.

Tell your doctor of any prescription and non-prescription medications, vitamins, supplements, and herbal products you are taking to prevent interactions with these medications. Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Aceon at room temperature (20-25°C)in a clean environment away from light and moisture, as well as out of reach from children and pets. Do not keep it in the bathroom. Always keep it in the container it came in and keep it tightly closed. Throw away unused or expired medications. Do not flush it in the toilet or down the sink. Consult your pharmacist on the proper disposal of this medication.

What action should I take in case of overdose?

In the event of an overdose, inform your doctor and seek immediate medical attention to prevent complications.

Is it safe for pregnant or breastfeeding women?

The use of Perindopril can cause harm to the fetus when given to pregnant women. According to the US FDA, Perindopril is categorized as Pregnancy Category D. If you are pregnant or become pregnant while taking Perindopril, discontinue taking the medication as soon as possible and inform your doctor immediately.

It is not known if Perindopril is excreted in human milk and if it will cause harm to the breastfeeding infant. Consult your doctor if you are breastfeeding an infant.

The use of Perindopril in pregnant and breastfeeding women should be avoided. However, the potential benefits may allow the use of the drug despite the possible risks.

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