Why is Actigall prescribed?

Ursodeoxycholic acid (Actigall) is being prescribed to help in the treatment of gallstones formed in the gall bladder due to an imbalance of bile and excess amount of cholesterol in the gall bladder.

What does it do?

Ursodeoxycholic acid, an anticholelithic agent, is a natural bile that works by decreasing the amount of cholesterol that is being used in the gall bladder, thus, help in dissolving gallstones.

How should I take it?

Actigall and its generic equivalents are available as 250mg capsule and 300mg scored tablet. It is intended for oral administration as a whole, not to be crushed or chewed, and should be taken with food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before using Actigall?

Before taking Ursodeoxycholic acid, tell your doctor or pharmacist if you have any allergies to food and to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems

Inform your doctor about your past and current medical history especially if you have or have had gall bladder diseases, acute cholecystitis, biliary obstruction, gallstone pancreatitis, cholangitis, liver disease and variceal bleeding

Avoid drinking alcohol as this may cause dizziness and drowsiness which can add to the effects of Ursodeoxycholic acid.

Certain laboratory tests such as gallbladder ultrasound test and other blood tests are highly recommended while using Ursodeoxycholic acid to monitor side effects that may affect your organs.

For the drug label information of Actigall, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Abdominal pain
• Back pain
• Chills
• Cough
• Diarrhea
• Dizziness
• Fatigue
• Flatulence
• Headache
• Increased liver function test
• Loss of hair

Serious side effects include:
• Chest pain
• Dysrhythmia 
• Dyspnea
• Leukopenia
• Peptic ulcer disease
• Peripheral edema
• Swelling of the lower layer of skin
• Thrombocytopenia

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Actigall with any of the following medications:

• Adalat
• Aldactone
• Amaryl
• Benicar
• Cholestyramine
• Claritin
• Clofibrate
• Colestipol
• Coumadin
• Crestor
• Crofelemer
• Floxin
• Heparin
• Losartan
• Metaglip
• Mestranol
• Naproxen
• Nicardipine
• Quinidine
• Reserpine
• Rosiglitazone
• Tirofiban
• Vinblastine
• Vincristine
• Zocor

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Actigall in room temperature(25°C)in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are no well-controlled studies and data with the use of Ursodeoxycholic acid in pregnant women. Therapeutic administration of the drug in the first trimester of pregnancy posted no evidence of effects in the unborn baby. However, as per US FDA, Ursodeoxycholic acid is categorized as Pregnancy category B which specifies that there are no known risks for animals, but no studies have been associated with humans.

The presence of Ursodeoxycholic acid in human milk is still unknown.

Consult your doctor before using this medication in pregnant women or in nursing infants.

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