Why is Activella prescribed?
Activella, a combination of Estradiol and Norethindrone, is used to prevent osteoporosis and symptoms of menopause such as hot flashes (sudden strong feelings of heat) and vaginal changes.
What does it do?
Activella is a combination of two drugs classified as hormones, namely: Estradiol, a type of estrogen and Norethindrone acetate, a form of progesterone. Both hormones are essential in regulating ovulation and menstruation. Estrogen is responsible for the development and maintenance of the female reproductive system, and the main source of estrogen is in the ovaries. Estrogen levels fall during menopause, hence producing symptoms like vaginal dryness and hot flashes.
How should I take it?
Activella is currently available as 1mg/0.5mg tablet taken whole (not split, chewed, or crushed) by mouth with or without food.
The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.
What if I missed a dose?
The proper use of medications is needed to achieve the desired effect of any drug. As much as possible, strictly follow your doctor’s prescribed dosing schedule. If you miss a dose, take it immediately. But if it is almost your next dose, skip the missed dose and proceed with the regular dosing schedule. Never take two doses at the same time to make up for a missed dose, unless told otherwise.
What are the special precautions before taking Activella?
Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Activella or any other ingredients included in the manufacture of this medication.
Inform your doctor if you had any form of surgery or if you are planning to get one.
For the drug label information of Activella, click here.
Does it have any side effects?
All medications can exhibit side effects and adverse reactions. Ask your doctor or pharmacist for more information.
Common side effects may include:
- Pain or tenderness felt on the breast
- Hair loss or unwanted hair growth
- Discoloration of the skin on the face
- Nausea, flatulence, abdominal pain
- Burning, itching, irritation, redness, or swelling of the vagina
- Weight gain
- Vaginal bleeding or spotting
Serious side effects may include:
- Breast mass
- Nipple discharge
- Abdominal pain, constipation
- Sudden severe headache
- Slurring of speech or memory loss
- Yellow discoloration of the skin or eyes
- Blisters, hives, itching, or rash
- Swelling of any part of the face or limbs
- Hoarseness, difficulty breathing or swallowing
- One-sided weakness or paralysis
Other side effects not listed above may be experienced when using Activella. If the symptoms do not go away or are life-threatening, immediately stop taking the medication and inform your doctor or call an ambulance for professional medical assistance.
Is it safe to take it with another drug?
Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Activella with any of the following medications:
- Betamethasone dipropionate
- Tranexamic acid
- St. John’s wort
Ask your doctor or pharmacist for other possible interactions not listed within this section.
How should I store it?
Keep Activella in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.
What should I do in case of an overdose?
Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.
Is it safe to take if I am pregnant or breastfeeding?
Activella is contraindicated for use in pregnant women, women trying to get pregnant, or breastfeeding women. It is not recommended when breastfeeding because it can be excreted in human milk and is known to decrease the amount and quality of milk production. Consider both the developmental and health benefits of breastfeeding, along with the mother’s clinical need for this medication.
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