Adcirca (Tadalafil) is a drug in the class of PDE5 enzyme inhibitors that blocks the enzyme, thereby relaxing blood vessels and increasing blood flow. It is used to treat pulmonary arterial hypertension to improve physical ability.

What does it do?

Adcirca (Tadalafil) is prescribed to treat high blood pressure in your lungs (pulmonary hypertension). This medication works by relaxes and widening the blood vessels in your lungs that allow the blood to flow easily and decreasing high blood pressure and improves your ability to exercise.

How should I take it?

Adcirca is for oral use. This medication tablet should be taken as per your doctor prescribed dosage with or without food. Do not split or split the tablets, as the recommended dose is 40 mg per day (two 20 mg tablets).

What if I missed a dose?

If you missed a dose, take it as soon you remember it and take the next dose at the regular time but do not double the dosage to catch up.

What are the special precautions before taking Adcirca?

Adcirca (Tadalafil) can cause hypotension (lower blood pressure) always inform your doctor if you have any preexisting cardiovascular disease before taking this medication.

This medication is not recommended for patients with pulmonary veno occlusive disease. Never take this medication with any nitrate, alpha-blocker, alpha-blocker drugs as your blood pressure could drop quickly and could get dizzy.

Tadalafil is also marketed for erectile dysfunction so please note not to take this in combination with other PDE5 inhibitors (Cialis) as an example.

Does it have any side effects?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Adcirca with any of the following medications:

Common side effects may include:
• Diarrhea
• Headache
• Muscle Pain
• Sore throat
Serious side effects may include:
• Painful and prolonged Erection
• Loss of vision
• Shortness of breath
• Seizures
• Ringing in your ears


If the symptoms do not go away or are life-threatening, immediately stop taking the medication and inform your doctor or call for professional medical assistance.

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Adcirca with any of the following medications:
• Alpha-Blockers (Alfuzosin, Doxazosin,Prazosin)
• Alcohol
• PDE5 inhibitors (Cialis)
• Ritonavir
• Nitrates (Isosorbide mononitrate,Isosorbide dinitrate)
• Grapefruit

Ask your doctor or pharmacist for other possible interactions not listed in this section.

How should I store it?

Adcirca should be stored at room temperature away from light and in the original package to protect from moisture.

What action should I take in case of overdose?

If severe symptoms shown like shortness of breath and non-arteritic anterior ischemic optic neuropathy (NAION) loss of blood flow to the optic nerve seek for an immediate medical attention.

Is it safe for pregnant or breastfeeding women?

Adcirca has not been shown to cause any harmful effects on fetal development during pregnancy and is to be used only when clearly needed. For nursing mothers, caution should be taken during this medication as this may pass into breast milk. Inform your doctor if you are pregnant or breastfeeding to avoid any complications.

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