Why is Aggrenox prescribed?

Aggrenox is often prescribed to reduce the risk of stroke in patients who have had blood clots or suffered from a mini stroke (transient ischemic attack). Clot formation predisposes a person to develop a stroke.

What does it do?

Aggrenox is a combination of Aspirin and Dipyridamole. Aspirin works by decreasing certain substances in the body that causes fever, inflammation, and pain. Dipyridamole, on the other hand, prevents platelets from sticking together to form clots.

How should I take it?

Aggrenox, along with its generic counterparts, comes in a 200mg/25mg capsule that must be taken whole (not opened, crushed, or chewed) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you forgot to take your medicine, immediately take the next dose to make up for the missed dose. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Never take two doses just to make up for your missed dose.

What are the special precautions before taking Aggrenox?

Taking this medication could cause excessive bleeding. Inform your doctor immediately if you experience sudden heavy bleeding anywhere in the body that does not stop.

Inform your doctor about all the medications you are taking, your current and previous medical history especially if you have asthma or bleeding disorders, and any allergic reactions to Aggrenox or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Aggrenox, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Diarrhea and abdominal pain
• Nausea
• Vomiting
• Headache
• Heartburn
• Muscle and joint pain

Serious side effects include:
• Sudden or worsening chest pain
• Lightheadedness or fainting
• Hearing problems
• Abdominal pain
• Dark discoloration of urine
• Bleeding in any part of the body (nosebleed, coughing blood/coffee ground material)
• Bloody or tar-like stools

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Aggrenox with any of the following medications:

• Avalide
• Avelox
• Celebrex
• Cosopt
• Coumadin
• Cozaar
• Diamox
• Diclofenac
• DDAVP
• Ibuprofen
• Insulin
• Isoptin
• Lexapro
• Lovenox
• Meloxicam
• Piroxicam
• Pradaxa
• Prednisone
• Probenecid
• Pulmicort
• Rheumatrex
• Rhinocort
• Tobradex

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Aggrenox in the container it came with and store in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Aggrenox is should not be used in pregnant women or women who are trying to get pregnant. However, there is still limited data on the developmental risks associated with the use of Aggrenox in pregnancy, its presence in human milk, or its effects on the breastfed infant. Hence, the potential risks and benefits of using Aggrenox in pregnant or breastfeeding women should be carefully considered.

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