Why is Aldactazide prescribed?

Aldactazide, a combination of Spironolactone and Hydrochlorothiazide, is used to manage hypertension. It is also used to manage fluid retention or edema associated with heart, liver, or kidney disease.

What does it do?

Spironolactone belongs to a class of medications called aldosterone receptor antagonists that causes the kidneys to eliminate excess water while retaining potassium from getting excreted along with the urine. Hydrochlorothiazide, on the other hand, is classified under diuretics or water pills that cause the elimination of excess water and sodium through the urine. Together both drugs work to provide relief of symptoms of hypertension and fluid retention.

How should I take it?

Aldactazide is currently available as 25mg/25mg and 50mg/50mg tablets taken whole (not split, chewed, or crushed) by mouth with or without meals.

The dosage strength and frequency will vary depending on your condition. Do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Aldactazide?

Aldactazide can cause drowsiness. Avoid driving and operating heavy machinery while taking this medication. Avoid the intake of alcohol while taking this medication as it can exacerbate drowsiness.

It is imperative that you inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Aldactazide, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Aldactazide, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Nausea
• Vomiting
• Changes in appetite
• Changes in bowel movement
• Abdominal pain
• Increase the frequency of urination
• Dizziness
• Headache
• Painful or enlarging breasts
• Menstrual irregularities
• Erectile dysfunction
• Vaginal bleeding

Serious side effects may include:
• Blisters, hives, itching, or rash
• Hoarseness, difficulty breathing or swallowing
• Swelling of any part of the eyes, face, or limbs
• Muscle weakness
• Rapid weight loss
• Fatigue
• Slow and irregular heartbeat
• Yellowish discoloration of eyes and skin
• Confusion
• Fever

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Aldactazide with any of the following medications:

• Abilify
• Alphagan
• Aminolevulinic acid
• Aspirin
• Avalide
• Azilect
• Azilsartan medoxomil
• Betrixaban
• Bystolic
• Carbegoline
• Celebrex
• Celexa
• Colchicine
• Coreg
• Cozaar
• Cymbalta
• Diazepam
• Diovan
• Eplerenone
• Ethanol
• Geodon
• Ginkgo
• Glucophage
• Haloperidol
• Hytone
• Insulin
• Invokana
• Lanoxin
• Lasix
• Lexapro
• Lisinopril
• Lithium
• Metaglip
• Morphine
• Multivitamin, prenatal
• Omeprazole
• Toprol
• Trazodone
• Norvasc
• Parenteral nutrition solution with electrolytes
• Potassium acetate
• Potassium acid phosphate
• Potassium bicarbonate
• Potassium chloride
• Potassium citrate
• Potassium gluconate
• Potassium quaiacolsulfonate
• Potassium perchlorate
• Potassium phosphate
• Proair
• Prograf
• Quinapril
• Ranexa
• Rapamune
• Restasis
• Topamax
• Ventolin
• Vitamin D3

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Aldactazide in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Spironolactone/Hydrochlorothiazide is not recommended for use in pregnant women, women trying to get pregnant, or are lactating women and should only be used if the benefits outweigh the risks associated with its use. Hence, the potential risks and benefits of using Aldactazide in pregnant or breastfeeding infants should be carefully considered.

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