Why is Asacol prescribed?

Asacol, with generic name Mesalamine, is prescribed to manage symptoms of ulcerative colitis, such as recurrent abdominal pain, diarrhea, rectal pain, and bleeding. Ulcerative colitis is a condition where there is irritation, swelling, and ulcers in the lining of the large intestine (colon) and rectum.

What does it do?

Mesalamine is an anti-inflammatory agent that reduces the inflammation of the lining of the large intestines and rectum, controlling the symptoms of ulcerative colitis.

How should I use it?

Asacol is currently available as 400mg and 800mg tablet taken whole (not split, chewed, or crushed) by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Asacol?

Avoid the intake of grapefruit or grapefruit juice while taking Asacol. If you are using Asacol Mycite, remove the patch if you are to undergo an MRI (magnetic resonance imaging) or any medical test involving powerful magnets. Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Asacol or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Asacol, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Chest pain
• Shortness of breath
• Blood or tar-like stools
• Bloody or coffee-ground vomitus
• Swelling of any part of the body

Serious side effects include:
• Itching, hives or rash without fever
• Hoarseness or difficulty of breathing
• Swelling of the abdomen or limbs
• Fatigue
• Appetite changes
• Abdominal pain
• Yellow discoloration of the skin or eye
• Pale skin
• Flu-like symptoms
• Headache or stiff neck
• Confusion
• Light sensitivity
• Muscle pain
• Discolored urine
• Vaginal discharge
• Difficult or painful urination

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Asacol with any of the following medications:

• Advil
• Amaryl
• Arthrotec
• Botulism immunoglobulin
• Cataflam
• Celebrex
• CMV immunoglobulin
• Deferasirox
• Diatrizoate
• Glimepiride
• Intravenous or subcutaneous Immunoglobulin
• Iodapamide
• Iodixanol
• Iohexol
• Iopamidol
• Iopramide
• Iothalamate
• Ioxaglate
• Ioxilan
• Ketorolac
• Lithium
• Methotrexate
• Metrizamide
• Naproxen
• Oxaliplatin
• Piroxicam
• RSV immunoglobulin
• Rho (d) immunoglobulin
• Streptomycin
• Tobradex
• Tolbutamide
• Vancomycin
• Varicella vaccine
• Voltaren
• Zoledronic acid

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Keep Asacol in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Mesalamine is acceptable for use if needed in pregnant women, women trying to get pregnant, and breastfeeding women. Plasma drug levels should be monitored regularly throughout pregnancy until the postpartum period. Still, the potential risks and benefits of using Asacol in pregnant or breastfeeding infants should be carefully considered.

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