Why is Axid prescribed?

Nizatidine (Axid) is prescribed for treatment and maintenance treatment of stomach and intestinal ulcers. It is also used in conditions where there is excess acid in the stomach, heartburn, and erosive esophagitis (damage to the esophagus due to the backing up of acid from the stomach).

What does it do?

Peptic ulcers (ulcers found in the stomach or intestine) occur when the stomach acid corrodes the lining of your stomach and decreases the mucus that protects it. Treatment of peptic ulcers are not difficult however if proper treatment is not done, they can worsen.

Nizatidine is a histamine-2 blocker and it decreases the amount of acid produced by the stomach. It can inhibit acid secretion at night for up to 12 hours and can also decrease acid secretion triggered by caffeine, food, and other causes.

How should I take it?

Axid is available in 150mg and 300mg capsules. It is intended for oral administration and should be swallowed as a whole. Do not crush, chew, break it in half, or tamper the capsule in any way. Take it with a full glass of water one hour before eating or drinking anything that may cause heartburn.

Follow your doctor’s instructions when taking Axid to ensure the best results. Only take the dose prescribed by your doctor and do not make alterations in the dosage or frequency when taking the medication.

If your heartburn worsens or your symptoms do not improve after 14 days, consult your doctor.

When taking Axid, you may need to make changes in your diet or lifestyle to improve your condition. Follow your doctor’s recommendations.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before taking Axid?

Inform your doctor if you are allergic to Nizatidine, any component of Axid, medications of the same category, or any other medications.

Inform your doctor of your past and present medical history if you have or have had pain when swallowing, heartburn that lasted more than 3 months, bloody or tarry stools, weight loss, vomiting, chest pain, stomach pain, and kidney or liver disease.

Tell your doctor if you have high levels of vitamin D and calcium in your blood, malabsorption syndrome (problems in absorbing nutrients from food) and if you are sensitive to large amounts of vitamin D.

Inform your doctor as well if you have ever had heart disease, diabetes, phenylketonuria, kidney disease, liver disease, or an electrolyte imbalance.

For the drug label information of Nizatidine, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Constipation
• Diarrhea
• Dizziness
• Headache
• Nasal congestion
• Runny nose

Serious side effects may include:
• Difficulty breathing
• Hives
• Skin itching
• Skin rashes
• Stomach pain
• Wheezing

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Nizatidine with any of the following medications:

• Amaryl
• Aminophylline
• Aspirin
• Atazanavir
• Cefpodoxime
• Cefuroxime
• Chlorpropamide
• Corlanor
• Crestor
• Cymbalta
• Dexilant
• Diabeta
• Gefitinib
• Glipizide
• Lapatinib
• Lasmiditan
• Lexapro
• Lipitor
• Naproxen
• Neratinib
• Nexium
• Nizoral
• Pazopanib
• Posaconazole
• Pradaxa
• Pregabalin
• Rilpivirine
• Selpercatinib
• Siponimod
• Sporanox
• Thalidomide
• Tolazamide
• Tolbutamide
• Uniphyl

Tell your doctor of any prescription and non-prescription medications, vitamins, supplements, and herbal products you are taking to prevent interactions with these medications. Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Axid at room temperature (20-25 °C) in a clean environment away from light and moisture. Do not keep it in the bathroom. Always keep it in the container it came in and keep it tightly closed. Keep out of reach from children and pets. Dispose medications that are no longer needed or expired. Do not discard it in the toilet or down the sink. Consult your pharmacist on the proper disposal of this medication.

What action should I take in case of overdose?

Some symptoms of overdose may include the following:

In the event of an overdose, inform your doctor and seek immediate medical attention.

Is it safe for pregnant or breastfeeding women?

There are no adequate and well-controlled studies of the use of Nizatidine in pregnant women. As per the US FDA, it is categorized as Pregnancy Category B and should only be given to pregnant women if clearly needed.

Nizatidine has been found in breast milk and should not be used by breastfeeding mothers unless consulted with a doctor.

Consult your doctor before using this medication in pregnant women or in nursing infants.

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