NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Baqsimi prescribed?

This medication is identical to the glucagon naturally produced by your body, which helps raise blood sugar levels by prompting the release of stored sugar from the liver. It is used to treat severe low blood sugar (hypoglycemia) when you may require assistance from others.

What does it do?

Baqsimi (Glucagon) functions by activating glucagon receptors in the liver, which triggers the breakdown of glycogen and the release of glucose into the bloodstream. It also prompts the liver to produce additional glucose from amino acids and reduces the liver's glucose consumption, allowing more glucose to be released into the blood. Additionally, Baqsimi slows digestion and influences fat tissue to enhance the breakdown of fat stores.

How should I take it?

Remove the glucagon spray from the package only when you're ready to use it. Gently place the tip of the spray nozzle into one nostril, then press the plunger firmly to administer the dose. This medication does not need to be inhaled to be effective. After administering the medication, seek medical help immediately. If the person is unconscious, turn them onto their side. If they don’t wake up within 15 minutes, another dose may be given, if available.

What if I missed a dose?

If you miss a dose of Baqsimi, it is important to use it as soon as you remember, but only if you are experiencing symptoms of severe low blood sugar. If you're not having symptoms, there's no need to use it.

What are the special precautions before taking Baqsimi?

Other medical conditions may impact the use of this medication. Be sure to inform your doctor if you have any of the following:

• Heart disease: Use with caution, as it may worsen the condition.
• Insulinoma (pancreatic tumor) or Pheochromocytoma (adrenal gland tumor): These conditions require special consideration.
• Prolonged fasting or starvation: This medication should not be used in patients with these conditions.

Glucagon can cause serious allergic reactions (anaphylaxis), which require immediate medical attention. Notify your doctor if you experience a rash, itching, hoarseness, trouble breathing or swallowing, swelling of the face, hands, or mouth, or fainting after using the medication.

If symptoms don't improve after consuming sugar, seek medical attention immediately. Do not engage in risky activities such as driving until your blood sugar is stabilized.

Does it have any side effects?
It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.
Commonside effects may include:
• High blood pressure: It may lead to high blood pressure in individuals with tumors in their adrenal glands.
• Headache
• Runny nose
• Nasal discomfort
• Nausea
• Stuffy nose
• Red eyes
• Vomiting
• Watery eyes
Serious side effects may include:
• High blood pressure: It may lead to high blood pressure in individuals with tumors in their adrenal glands.
• Low blood sugar: In some people with tumors in their pancreas,Baqsimi may cause low blood sugar.
• Severe allergic reaction
These are not all the possible side effects of Baqsimi. For more details, consult your doctor. If you have concerns about side effects, contact your doctor for medical advice.
Is it safe to take it with another drug?

Medications that interact with Baqsimi may reduce its effectiveness, alter its duration of action, increase side effects, or diminish its effects when taken together. Consult your doctor about how to manage drug interactions.

Common medications that may interact with Baqsimi include:

• Beta-blockers, such as Propranolol, Atenolol, Sotalol, or Timolol (which may cause a temporary increase in blood pressure and heart rate)
• Indomethacin (which may interfere with Baqsimi's ability to raise blood sugar levels and could cause hypoglycemia)
• Warfarin (which may enhance the anticoagulant effect)
This list includes only some common medications that may interact with Baqsimi. Inform your doctor of all the medications you are using.
How should I store it?
Store the device at room temperature, away from light and moisture. Only unwrap it when you're ready to use it. Keep all medications out of reach of children and pets.
What action should I take in case of overdose?
If someone overdoses and experiences severe symptoms like fainting or difficulty breathing, seek immediate medical attention or go to the nearest hospital.
Is it safe for pregnant or breastfeeding women?
Inform your doctor if you are pregnant before using this medication and it is unclear whether this drug passes into breast milk, but it is unlikely to harm a breastfeeding infant. Speak with your doctor before breastfeeding.
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