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Why is Biltricide prescribed?

Biltricide is used to treat schistosomiasis, a chronic parasitic infection in humans caused by blood flukes (worms).

What does it do?

Biltricide eliminates blood flukes by causing their immediate contraction and paralysis while also preventing them from absorbing and utilizing sugars. The parasite is then broken down by white blood cells and expelled from the body.

How should I take it?

Swallow this medication with a glass of water, following the instructions on your prescription label. Take it with food, and do not chew, crush, or dissolve it in your mouth before swallowing. Tablets may be split along the score lines if instructed by your doctor. Take the medication at evenly spaced intervals and only as prescribed. Complete the full course, even if you feel better, and do not skip doses or stop early.

What if I missed a dose?

Take Biltricide consistently at the same time each day. If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double dose. If you are unsure, consult your doctor for guidance.

What are the special precautions before taking Biltricide?

Inform your doctor about all the medications you are taking, your current and previous medical history. Additional information may be obtained when you ask your doctor or pharmacist.

Do Not Use Biltricide If:

• The infestation affects your eyes, as killing the parasite in this area may lead to blindness.
• You are allergic to praziquantel or any of the listed ingredients.
• You are taking rifampicin (an antibiotic for tuberculosis or leprosy), dexamethasone (a corticosteroid), or anti-epileptic medications.

Biltricide use may worsen your medical condition, causing symptoms similar to an allergic reaction. This is more common in the acute phase of schistosomiasis when the worms start producing eggs. Severe complications, such as lung failure, encephalopathy (brain disease), or cerebral vasculitis (narrowing/blockage of brain blood vessels), may occur.

If treating an infestation in the brain or spinal cord, you may experience severe headaches and seizures. If your doctor recommends treatment for brain infestation, hospitalization and specialist monitoring may be necessary. Your doctor may decide to closely monitor you or admit you to a hospital while you are on Biltricide.

If you have not already informed your doctor or pharmacist of any of these conditions, make sure to do so before starting Biltricide. Be aware of potential side effects and understand how to monitor them during treatment.
Does it have any side effects?
It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.
Common side effects may include:
• Dizziness or drowsiness
• Headache
• Loss of appetite
• Stomach discomfort, including nausea
Serious side effects may include:
• Allergic reactions, including itching, hives, rash, or swelling of the lips, face, or tongue
• Fever
• Bloody diarrhea
• Breathing difficulties
• Rapid or irregular heartbeat
• Seizures
This is not a complete list of possible side effects. Contact your doctor for medical advice if you experience any concerning symptoms.
Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Biltricide with any of the following medications:

Do not take Biltricide if you are using:

• Rifampicin, an antibiotic for tuberculosis and leprosy
• Efavirenz, a medication for HIV treatment

Certain medications may interact with Biltricide and alter its effectiveness, including:

• Chloroquine, an antimalarial drug
• Cimetidine, used to treat acid reflux and ulcers
• Grapefruit juice
• Dexamethasone, an anti-inflammatory and immunosuppressant
• Epilepsy medications
• Erythromycin, an antibiotic for bacterial infections
• Ketoconazole or itraconazole, antifungal treatments
• Ritonavir, an HIV medication
These substances may impact how Biltricide works or how your body processes it. Your doctor may need to adjust your dosage or prescribe alternative treatments.
How should I store it?
Store at room temperature below 30°C (86°F), away from heat and direct light. Dispose of any unused medication after the expiration date.
What action should I take in case of overdose?
If you suspect an overdose, seek immediate medical attention by contacting a poison control center or visiting the nearest emergency room.
Is it safe for pregnant or breastfeeding women?
Biltricide should only be used during pregnancy if prescribed by a doctor. This medication passes into breast milk, so breastfeeding is not recommended while using it. Nursing mothers should discontinue breastfeeding on the day of treatment and for 72 hours after the final dose.
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