Why is Colcrys prescribed?

Colchicine (Colcrys) is indicated in gout and as gout attacks prophylaxis. It is also used in adults and children over four (4) years old with Familial Mediterranean fever (FMF).

What does it do?

Patients with gout usually experience pain in their joints in some parts of their bodies. Colchicine acts by interrupting the inflammation pathways thereby alleviating the symptoms of gout attacks. However, at present, the mechanism of action of Colchicine in FMF has not been clearly established.

How should I take it?

Colcrys is currently available in a 0.6mg tablet which can be taken by mouth, with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Colcrys?

Inform your doctor about all the medications you are taking, your current and previous medical history especially if you have or had kidney and liver impairments and if you have any allergies to Colchicine or any other ingredients included in the manufacture of this medication.

Infertility has been experienced by male patients in some studies, ask your doctor for more information.

Avoid taking Colcrys with grapefruit juice.

For the drug label information of Colcrys, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Headache
• Nausea
• Dizziness
• Vomiting
• Joint pain

Serious side effects may include:
• Bleeding or Bruising
• Discoloration of the lips, tongues or palms (graying)
• Difficulty of breathing
• Swelling in any part of the body
• Rashes or Hives

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Colcrys with any of the following medications:

• Azithromycin
• Bezafibrate
• Biaxin
• Cardizem
• Crixivan
• Diflucan
• Emend
• Erythromycin
• Invirase
• Isoptin
• Lanoxin
• Lescol
• Lipitor
• Lofibra
• Lopid
• Mevacor
• Nefazodone
• Neoral
• Pravachol
• Ranexa
• Ritonavir
• Sporanox
• Tricor
• Viracept
• Zocor

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Colcrys in a tight container, in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

At present, it has not been established if Colchicine is associated with risks for birth defects, miscarriage, or adverse maternal or fetal outcomes.

There is no available data that Colchicine affects milk production, however, it may be present in human milk. Immediately inform your doctor if you are pregnant or planning to get pregnant to check if you can take the medication or not.

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