Why is Cymbalta prescribed?

Cymbalta (Duloxetine) is prescribed to manage depression and generalized anxiety disorder (excessive anxiety that disrupts daily functions lasting six months or longer) in adults and children seven years and older. It can also be used to treat diabetic neuropathy, which manifests as pain and tingling on the extremities. It is also prescribed to manage the symptoms of fibromyalgia (painful muscle stiffness) in adults and children thirteen years and above, as well as symptoms of osteoarthritis such as joint pain or back pain.

What does it do?

Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRIs), which increases the levels of serotonin and norepinephrine in the brain that aids in maintaining mental balance and suppresses pain signals.

How should I use it?

Cymbalta is currently available as 30mg and 60mg delayed-release capsule, taken whole (not split, chewed, or crushed) with food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Cymbalta?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Cymbalta or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Cymbalta, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Nausea and vomiting
• Urinary and Bowel movement changes
• Appetite changes
• Dry mouth
• Headache
• Dizziness
• Fatigue
• Muscle cramps or pain
• Changes in libido
• Uncontrollable shaking

Serious side effects may include:
• Yellow discoloration of skin and eyes
• Difficulty of breathing or swallowing
• Swelling on any part of the face or limbs
• Flu-like symptoms
• Abdominal distention
• Easy bruising or bleeding
• Discoloration of urine
• Confusion

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Cymbalta with any of the following medications:

• Abilify
• Adderall
• Advil
• Ambien
• Amitriptyline
• Ativan
• Azilect
• Celexa
• Cipro
• Flexeril
• Gabapentin
• Granisetron
• Klonopin
• Lexapro
• Lyrica
• Methylene blue
• Mirtazapine
• Neurontin
• Nexium
• Nolvadex
• Norco
• Ondansetron
• Pristiq
• Prozac
• St. John’s wort
• Sumatriptan
• Tramadol
• Trazodone
• Wellbutrin
• Xanax
• Zolmitriptan
• Zoloft

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Cymbalta in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Cymbalta is not advisable for use in pregnant women, women trying to get pregnant, or breastfeeding women. Hence, the use of Cymbalta in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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