Why is Daliresp prescribed?

Daliresp, with the generic name Roflumilast, is used to control episodes and prevent worsening symptoms of chronic obstructive pulmonary disease (COPD; emphysema and chronic bronchitis) like chest tightness, difficulty of breathing, and wheezing.

What does it do?

Roflumilast belongs to a class of medications called Phosphodiesterase inhibitors which decreases the inflammation and swelling in the lungs to reduce the episodes and prevent the worsening of symptoms of COPD.

How should I take it?

Daliresp is currently available as a 250mg and 500mg tablet taken whole (not split, chewed, or crushed) by mouth with food. Daliresp only controls and prevents the symptoms of COPD and does not cure it. Do not discontinue taking this medication unless told otherwise by your doctor.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Daliresp?

Daliresp is not a rescue medication for acute attacks of COPD. In the case of acute attacks, use the rescue medication or inhaler prescribed by your doctor.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Daliresp, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Daliresp, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Diarrhea
• Nausea
• Dizziness
• Headache
• Back pain
• Nausea
• Muscle spasms
• Changes in appetite
• Uncontrollable movements

Serious side effects may include:
• Itching, hives, or rash
• Swelling on any part of the face
• Hoarseness
• Difficulty breathing or swallowing
• Rapid, irregular heartbeat
• Anxiety
• Depression
• Sleep disturbance
• Eye pain
• Chest pain or tightness
• Wheezing

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Daliresp with any of the following medications:

• Anakinra
• Azathioprine
• Bexarotene
• Carbamazepine
• Cimetidine
• Cipro
• Cladribine
• Cordarone
• Deferasirox
• Diflucan
• Erythromycin
• Fosphenytoin
• Grepafloxacin
• Hytone
• Ifosfamide
• Interferon-alfa
• Isoniazid
• Loratinib
• Lutetium Lu 177 Dotatate
• Methotrexate
• Mycophenolate mofetil
• Nizoral
• Oxaliplatin
• Peginterferon-alfa
• Prograf
• Pulmicort
• Prednisolone
• Rapamune
• Rhinocort
• Sporanox
• St. John’s wort
• Theophylline
• Vfend

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Daliresp in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Roflumilast is not recommended for use in pregnant women, women trying to get pregnant, or who are breastfeeding. Hence, the potential risks and benefits of using Daliresp in pregnant or breastfeeding infants should be carefully considered.

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