Why is DDAVP prescribed?

Desmopressin (Ddvap) is prescribed for the treatment of certain kinds of injury such as head and brain injury that causes loss of bladder control in patients suffering from diabetes insipidus.

What does it do?

Desmopressin, classified as vasopressin-related hormone, primarily works by increasing the permeability of water in the tubules of the renal cells; thus, reducing the volume of urine in the bladder and prevents dehydration.

How should I take it?

Ddvap and its generic equivalents are currently available as a 0.1mg and 0.2mg tablets that should be taken as a whole (do not split) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before using Ddvap?

Inform your doctor about your past and current medical history, especially if you have or have had heart failure, low levels of sodium in the blood, sever kidney disease, psychological disorder that increases urge to thirst, uncontrolled blood pressure, cystic fibrosis, fluid retention and syndrome of inappropriate antidiuretic hormone secretion.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Desmopressin, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Dizziness
• Dry mouth
• Headache
• Hyponatremia
• Nausea
• Mild abdominal pain

Serious side effects include:
• Confusion
• Dyspnea
• Flushing
• Hallucinations
• Loss of muscle coordination
• Muscle cramps
• Restlessness
• Swelling
• Syncope
• Vomiting
• Weakness

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Ddavp with any of the following medications:

• Abilify
• Acarbose
• Acebutolol
• Acetazolamide
• Acyclovir
• Amvasc
• Asendin
• Aspilet
• Auvi-Q
• Aztram
• Benzphetamine
• Bretylium
• Buspirone
• Candez
• Capomed
• Carbatrol
• Carbidopa
• Carboplatin
• Chlorpropamide
• Concore
• Dexmethylphenidate
• Dobulex
• Dopamine
• Elavil
• Ephedrine
• Fenfluramine
• Isoproterenol
• Levodopa
• Levophed
• Lioresal
• Lotensin
• Mometasone
• Norvasc
• Phentermine
• Propylhexedrine
• Symmetrel
• Tenormin
• Xanor
• Yohimbine

If you are using any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Ddavp at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Desmopressin to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.

Limited data have been established indicating the presence of Desmopressin in human milk. Consult your doctor first before breastfeeding.

The use of Desmopressin in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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