Why is Desyrel prescribed?

Trazodone (Desyrel) is prescribed for the treatment of depression that may affect a person’s mood, energy levels, anxiety, appetite and insomnia.

What does it do?

Trazodone, classified as an anti-depressant medication, primarily works by blocking the reuptake of certain neurotransmitters such as Serotonin; thus, helping the restoration of the balance of chemicals in the brain.

How should I use it?

Desyrel and its generic equivalents are available 50mg, 75mg, 100mg and 150mg tablets. It is intended for oral administration as a whole, not to be crushed or chewed, and should be taken with food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before using Desyrel?

Before taking Trazodone, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had thrombocytopenia, breathing problems, closed-angle glaucoma, asthma, coronary artery disease, seizure, overactive thyroid, neuroblastoma, ileus, kidney problems, liver problems and schizophrenia and dysrhythmia.

Avoid drinking alcohol as this may cause dizziness and drowsiness which can add to the effects of Trazodone.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Tradozone, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Blurred vision
• Diarrhea
• Dizziness
• Drowsiness
• Fatigue
• Nausea
• Stuffy nose
• Swelling
• Vomiting
• Weight loss

Serious side effects include:
• Agranulocytosis
• Dark colored urine
• Depression
• Enlargement of breast
• Hallucinations
• Hyperglycemia
• Irregular menstruation
• Leukopenia
• Priapism
• Swollen lymph nodes
• Thrombocytopenia
• Unwanted breast milk production

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Desyrel with any of the following medications:

• Abilify
• Aliskiren
• Almotriptan
• Anafranil
• Arsenic trioxide
• Asendin
• Aspirin
• Budesonide
• Butorphanol
• Carbatrol
• Cataflam
• Celebrex
• Chlorpheniramine
• Clonazepam
• Cimetidine
• Cyclizine
• Dantrolene
• Dexamet
• Diflucan
• Dilzem
• Disopyramide
• Droperidol
• Elavil
• Lanoxin
• Lioresal
• Prozac
• Tagamet
• Virlix
• Voltaren
• Xanor
• Zithromax

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Desyrel in room temperature (25°C) in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Trazodone to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. However, as per US FDA,Trazodone categorized as Pregnancy Category C which states that no potential harm and well-controlled studies have been done in humans; but animal studies have shown adverse effects on the fetus.

Limited data have been established indicating the presence of Trazodone in human milk. Consult your doctor first before breastfeeding.

The use of Trazodone in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks

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