NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Diacomit prescribed?

Diacomit (Stiripentol) is prescribed for the treatment of seizures associated with Dravet syndrome in patients who are 6 months of age or older, weigh at least 15 pounds, and are already taking Clobazam.

What does it do?

Diacomit works in combination with other anti-seizure medications, particularly Clobazam, to help reduce the frequency and severity of seizures in patients with Dravet syndrome. By modulating neurotransmitter activity in the brain, Diacomit helps to stabilize brain function and prevent seizures.

How should I take it?

Follow all instructions on your prescription by your provider the dose depends on the age and body weight. Always take this medicine with a meal and swallow the capsule whole do not crush, chew, break, or open it.

What if I missed a dose?

Take the medicine as soon as you remember, but if it's nearly time for your next dose, skip the missed dose. Do not double dose.

What are the special precautions before taking Diacomit?

Diacomit should not be given to children younger than 6 months old. To ensure Diacomit is safe for you, inform your doctor if you have a history of:

• Alcohol use
• Liver or kidney disease
• Depression or other mood disorders
• Suicidal thoughts or actions

A small number of people may experience thoughts of suicide while taking Diacomit. Your doctor will monitor your progress during regular visits, and your family or caregivers should also be alert to any changes in your mood or symptoms.

The powdered form of this medicine may contain Phenylalanine. Let your doctor know if you have Phenylketonuria (PKU).

Does it have any side effects?

Notify your doctor if you notice any new or worsening symptoms, such as changes in mood or behavior, anxiety, restlessness, trouble sleeping, aggression, or thoughts of self-harm or suicide.

Common side effects may include:
• Agitation
• Balance or muscle movement problems
• Drowsiness
• Nausea
• Muscle weakness
• Weight loss
Serious side effects may include:
• Easy bruising or unusual bleeding
• Low white blood cell count, with symptoms like skin sores, or trouble breathing
• Significant weight loss
• Severe drowsiness
This is not a complete list of side effects, and others may occur. Contact your doctor for advice on any side effects you experience.
Is it safe to take it with another drug?
Sometimes, it’s not safe to take certain medications together. Some drugs can affect the levels of other medications in your blood, which may increase side effects or reduce the effectiveness of the treatments.
• Caffeine
• Carbamazepine
• Clopidogrel
• Diazepam
• Theophylline
• Glyburide
Taking Diacomit with other drugs that cause drowsiness can intensify this effect. Before using muscle relaxers, opioid medications, sleeping pills, or drugs for seizures or anxiety, consult your doctor.
How should I store it?
Store in the original package at 20°C to 25°C to protect from light. Keep out of reach of children.
What action should I take in case of overdose?
If you have taken too much Diacomit and shows serious symptoms like fainting or difficulty breathing, contact your doctor or go to the nearest emergency room immediately.
Is it safe for pregnant or breastfeeding women?
Inform your doctor if you are pregnant or planning to become pregnant before taking Diacomit, as it may harm a fetus. A pregnancy exposure registry tracks pregnancy outcomes in women who have been exposed to AEDs, like Diacomit, during pregnancy. It is unclear whether Diacomit passes into breast milk. Consult your doctor before breastfeeding to discuss the potential risks and benefits.
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