Why is Diane 35 prescribed?

Ethinyl estradiol and Cyproterone (Diane 35) is prescribed for the treatment of skin conditions such as acne associated with seborrhea (oily skin) and mild hirsutism (excessive hair growth) in women. It can also be used as an oral contraceptive to prevent pregnancy.

What does it do?

Acne is a condition where the hair follicles on your skin become blocked with dirt, oil, and dead skin cells causing pimples, whiteheads, and blackheads. Diane 35 contains two medications Ethinyl estradiol and Cyproterone. Ethinyl estradiol belongs to a drug class called estrogens and works by reducing the levels of androgens (male hormone) in the blood. Cyproterone belongs to a drug class called anti-androgens and it works by blocking the production of androgens.

How should I take it?

Diane 35 and its generic equivalents are currently available in 0.35/2mg tablets. Each tablet should be taken as a whole (do not split) by mouth, with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, you may need to follow special instructions depending on which tablet and how much you missed. Consult your doctor or pharmacist if you have any concerns regarding the instructions.

What are the special precautions before taking Diane 35?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Diane 35 or any other ingredients included in the manufacture of this medication.

Taking Diane 35 can cause your skin to be more sensitive to sunlight. Avoid exposing yourself to excessive amounts of sunlight and wear protective clothing, sunscreen, and use sunglasses when going outdoors.

Taking Diane 35 will not prevent the transmission of sexually transmitted diseases. Make sure to use a condom for protection.

For the drug label information of Diane 35, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Breast tenderness
• Headaches
• Mood swings
• Period pains
• Stomach pains
• Weight gain or loss

Serious side effects include:
• Bloody urine
• Chest pain
• Confusion
• Dizziness
• Fatigue
• Leg warmth
• Nausea and vomiting
• Pain when walking or standing
• Vision problems
• Yellowing of the skin or eyes

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Diane 35 with any of the following medications:

• Acefylline
• Amobarbital
• Amprenavir
• Auralgan
• Beclamide
• Benicar
• Betrixaban
• Bexarotene
• Butalbital
• Canagliflozin
• Crizotinib
• Dalteparin
• Diamox
• Dilantin
• Entecavir
• Famvir
• Griseofulvin
• Ibrutinib
• Isotretinoin
• Lamisil
• Lanoxin
• Lobucavir
• Lopinavir
• Luvox
• Monteplase
• Nefazodone
• Nilotinib
• Noscapine
• Ombitasvir
• Orphenadrine
• Paritaprevir
• Prevacid
• Quinidine
• Rapamune
• Rifampicin
• Saquinavir
• Seroquel
• Sulodexide
• Teniposide
• Vfend
• Xatral
• Zomig
• Zovirax

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Diane 35 in its container in a clean environment away from excessive heat and moisture.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Present data suggest that the use of Diane 35 in pregnant women is contraindicated. It should not be taken when pregnancy is confirmed as it can cause harm to the fetus.

There is also limited data on the presence of Diane 35 in human milk or its effects on the breastfed infant.

The use of Diane 35 in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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