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Why is Dibenzyline prescribed?

Dibenzyline (Phenoxybenzamine) is often prescribed to manage high blood pressure and excessive sweating in individuals with a rare tumor known as Pheochromocytoma.

What does it do?

Dibenzyline is an alpha blocker that helps relax and widen the blood vessels in your body, allowing blood to flow more easily and lowering blood pressure. It also reduces sweating by blocking the action of specific nerve signals throughout the body, including those that stimulate the sweat glands.

How should I take it?

Take Dibenzyline by mouth, following the instructions on the prescription label. Take your doses at consistent intervals and do not take more than prescribed. Only stop taking it if your doctor or healthcare provider advises you to.

What if I missed a dose?

If you miss a dose of Dibenzyline, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and take only the scheduled one. Do not take two doses at once.

What are the special precautions before taking Dibenzyline?

Inform your doctor about all the medications you are taking, your current and previous medical history.

Let your doctor know if you have any of the following conditions.

• Shock
• Stroke
• Kidney disease
• Heart or circulatory disease
• An allergic or unusual reaction to phenoxybenzamine
• Are breastfeeding
• Are pregnant or trying to become pregnant

Drowsiness and dizziness are more likely after your first dose, after a dose increase, or in hot weather or during exercise. Avoid driving or engaging in activities that require mental focus until you know how this medication affects you.

Does it have any side effects?
It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.
Common side effects may include:
• Drowsiness
• Fatigue
• Upset stomach
• Rapid heartbeat
• Small pupils
Serious side effects may include:
• Low Blood Pressure Upon Standing (Orthostatic Hypotension)

There may be other side effects of Dibenzyline not listed here. Contact your healthcare provider if you suspect you are experiencing any side effect.

Is it safe to take it with another drug?
Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Dibenzyline with any of the following medications:
• Epinephrine
• Reserpine
• Medicines for high blood pressure
• Medications for colds and respiratory issues
• Medications for erectile dysfunction (ED) such as Sildenafil
• Other alpha-blockers like Phentolamine, Alfuzosin, Doxazosin, and Terazosin

This list may not include all possible interactions. Be sure to provide your healthcare provider with a complete list of all medications, herbs, over-the-counter drugs, or dietary supplements you are taking.

How should I store it?
Store the medication at 15° to 30°C room temperature, away from heat, moisture, and direct light.
What action should I take in case of overdose?
Overdose of this medication can cause postural hypotension, immediately discontinue the medication and as needed go to the nearest emergency room.
Is it safe for pregnant or breastfeeding women?

It is unclear whether Phenoxybenzamine can affect pregnancy or harm an unborn baby. Inform your healthcare provider if you are pregnant or planning to become pregnant. Phenoxybenzamine passes into breast milk. Let your healthcare provider know if you are breastfeeding or planning to breastfeed.

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