Why is Emend prescribed?

Aprepitant (Emend) is prescribed along or in combination of other medications for the management of nausea and vomiting that is associated in chemotherapy.

What does it do?

Aprepitant, classified as an anti-emetic medication, primarily works by blocking in the central and peripheral nervous system the neurokinin 1 substance which is responsible for vomiting.

How should I take it?

Emend and its generic equivalents are currently available as 125mg and 80mg capsules that should be taken as a whole (do not split) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Emend?

Before taking Aprepitant, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had liver disease, kidney disease and cancer.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Emend, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Abnormal liver function tests
• Abdominal pain
• Dizziness
• Dehydration
• Headache
• Hiccups
• Indigestion
• Itching
• Loss of appetite
• Restlessness

Serious side effects include:
• Chills
• Cold hands and feet
• Dry skin
• Dyspnea
• Easy bruising
• Fever
• Low white blood cell count
• Pain in urination
• Skin sores
• Soreness of throat
• Syncope
• White patches in the mouth

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Emend with any of the following medications:

• Abametapir
• Abilify
• Apalutamide
• Biaxin
• Carbatrol
• Cardepine
• Chloramphenicol
• Cimetidine
• Cobicistat
• Colchicine
• Coralan
• Cordarone
• Darunavir
• Diflucan
• Dilantin
• Dilzem
• Dronedarone
• Ergotamine
• Erythromycin
• Fentanyl
• Flibanserin
• Flomax
• Griseofulvin
• Ifosfamide
• Isoniazid
• Isoptin
• Lipitor
• Mefloquine
• Mevacor
• Pimozide
• Plavix
• Plogrel
• Prozac
• Ranolazine
• Ritonavir
• Samsca
• Saquinavir
• Serzone
• Simvaz
• Sinemet
• Sirolimus
• Sporanox
• Tagamet

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Emend at room temperature (25 °C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Aprepitant to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.

Limited data have been established indicating the presence of Aprepitant in human milk. Consult your doctor first before breastfeeding.

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