Why is Estrogel prescribed?

Estrogel, with the generic name Estradiol, is a topical gel used to treat and prevent symptoms of menopause in women who are or are undergoing menopause.

What does it do?

Estradiol, a form of estrogen, is a naturally occurring hormone in the body that typically decreases once menopause begins. Estradiol works as a replacement for estrogen that is normally produced in the body, providing relief of symptoms such as hot flashes (sudden strong feelings of heat) and vaginal changes such as dryness, itching, or burning sensation.

How should I apply it?

Estrogel is currently available as 0.06% topical gel applied on the skin of one arm, starting from the wrist to the shoulder. Do not apply this gel on the breasts or on dry, irritated skin.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before applying Estrogel?

Avoid smoking or going near fire or open flame until Estrogel has completely dried, as this medication can catch fire.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Estrogel, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Estrogel, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Pain or tenderness felt on the breast
• Hair loss or unwanted hair growth
• Discoloration of the skin on the face
• Nausea, flatulence, abdominal pain
• Burning, itching, irritation, redness, or swelling of the vagina
• Vaginal bleeding, spotting, or discharge
• Vaginal irritation or swelling
• Changes in libido
• Weight changes
• Mood changes
• Dysmenorrhea
• Sleep disturbance

Serious side effects may include:
• Blisters, hives, itching, or rash
• Hoarseness, difficulty breathing or swallowing
• Swelling of any part of the face or limbs
• Yellow discoloration of the skin or eyes
• Uncontrollable movement
• Bulging of the eyes
• Fever
• Bulging eyes

Is it safe to apply it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Estrogel with any of the following medications:

• Actoplus
• Augmentin
• Azithromycin
• Betamethasone
• Biaxin
• Boceprevir
• Carfilzomib
• Cefaclor
• Coumadin
• Cardizem
• Dantrolene
• Diflucan
• Emend
• Erythromycin
• Flagyl
• Hemin
• Hytone
• Invokana
• Insulin
• Lenalidomide
• Lipitor
• Metaglip
• Nizoral
• Phenobarbital
• Pomalidomide
• Prograf
• Pulmicort
• Ranexa
• Rhinocort
• Sporanox
• St. John’s wort
• Thalidomide
• Tranexamic acid
• Insulin
• Synthroid
• St. John’s wort
• Valproic acid
• Vancomycin
• Vfend

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Estrogel in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Estradiol is contraindicated for use in pregnant women, women trying to get pregnant, or are breastfeeding. Hence, the potential risks and benefits of using Estrogel in pregnant or breastfeeding infants should be carefully considered.

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