Why is Evalon prescribed?

Estriol (Evalon) vaginal cream is indicated in female patients with vaginal atrophy due to a decrease in estrogen levels during menopause. It is also used to help in wound healing in vaginal surgery.

What does it do?

Evalon belongs to a class of medications called Hormone Replacement Therapy. It contains a naturally occurring estrogen, which aids in restoring the vaginal tissue to prevent symptoms such as dryness, itching and inflammation. This action can also increase resistance to bacterial infections in the vagina and urinary tract.

How should I use it?

Evalon is currently available as a 1mg vaginal cream in 15g tubes. It comes in a pack along with a plastic applicator.

Evalon is a vaginal cream intended for insertion into your vagina, with the use of the applicator provided. This should be done, ideally, before bedtime.

To apply the vaginal cream:

• Remove the cap of the tube, turn it upside down and use the sharp tip to open the tube. Then attach the applicator onto the tube.
• Squeeze the tube until the applicator is filled up to the ring mark. Then detach the applicator from the tube and place the cap back on.
• Lie down on your back and insert the applicator deep into your vagina and slowly push the plunger all the way in.

It is imperative to use Evalon according to your doctor’s prescription. Do not stop taking the medication even if your symptoms appear to be improving. Use Evalon only for the recommended duration and amount prescribed.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before using Evalon?

Inform your doctor about all the medications you are taking, your current and previous medical history such as high blood pressure or have a high risk of getting blood clots, asthma, diabetes, liver or kidney problems and if you have any allergies to Estriol, Estradiol or any other ingredients included in the manufacture of this medication

Inform your doctor if you are planning on getting any form of surgery.

For the drug label information of Evalon, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Vaginal irritation
• Vaginal itching
• Breast tenderness
• Anxiety
• Nausea
• Flatulence
• Stomach upset

Serious side effects include:
• Loss of consciousness
• Thromboembolism

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Evalon with any of the following medications:

• Carbatrol ER
• Griseofulvin
• Hytone
• Nevirapine

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Evalon vaginal cream in a cool dry place below 25°C. Keep away from direct sunlight. Do not refrigerate.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

Although there are limited studies in humans, Evalon vaginal cream maybe unsafe to use during pregnancy. Animal studies have shown harmful effects on the developing baby.

It can be excreted in human milk. However, its effects on the infant are still not fully known. Hence, it is essential to consider both the developmental and health benefits of breastfeeding, along with the mother’s clinical need for this medication.

In addition, Evalon vaginal cream is probably unsafe for breastfeeding. Limited data shows that the drug may pass into the breast milk and could harm the baby.

Inform your doctor if you are pregnant or breastfeeding or planning on doing so to ensure that the benefits of taking the medication outweigh the risks.

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