Why is Femara prescribed?

Femara, with generic name Letrozole, is used to treat early breast cancer in menopausal women or women who have undergone radiation, surgical removal of the tumor, or have previously taken Tamoxifen (Nolvadex) for 5 years.

What does it do?

Letrozole belongs to a class of medications called non-steroidal aromatase inhibitors, which decreases estrogen production to slow down or halt the growth of estrogen-dependent breast cancer.

How should I take it?

Femara is currently available as a 2.5mg tablet taken whole (not split, chewed, or crushed) taken by mouth, with or without food. This medication is usually taken for several years or longer. Do not stop taking Femara unless told otherwise by your doctor.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Femara?

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Femara or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Femara, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Nausea
• Bowel movement changes
• Appetite changes
• Sleep disturbance
• Weight changes
• Swelling of limbs
• Vaginal bleeding or irritation
• Breast pain
• Nausea
• Vomiting
• Abdominal pain
• Hair loss
• Blurring of vision

Serious side effects may include:
• Severe abdominal pain felt on the upper right side
• Yellowish discoloration of the eyes or skin
• Fu-like symptoms
• Hives, itching, or rash
• Easy bruising
• Unusual bleeding
• Severe headache
• Chest pain
• Sudden slurring of speech
• Sudden one-sided weakness or numbness
• Problems in memory and cognition

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Femara with any of the following medications:

• Apalutamide
• Bexarotene
• Boceprevir
• Bosentan
• Brigatinib
• Cannabidiol
• Celexa
• Ceritinib
• Climara
• Deferasirox
• Echinacea
• Fosaprepitant
• Fostamatinib
• Emend
• Hydroxyprogesterone
• Lapatinib
• Lexapro
• Mifepristone
• Nilotinib
• Oxycarbazepine
• Premarin
• Prempro
• Prograf
• Provera
• Quinestrol
• Rapamune
• Rucaparin
• St. John’s wort
• Telithromycin
• Temsirolimus
• Thalidomide
• Vivelle dot

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Femara in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Letrozole is contraindicated for use in pregnant women, women trying to get pregnant, and breastfeeding women. Hence, the potential risks and benefits of using Femara in pregnant or breastfeeding infants should be carefully considered.

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