NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Gemtesa prescribed?

Gemtesa (Vibegron) is a prescription medication used to treat symptoms of overactive bladder in adults, as well as symptoms in adult men who are taking medication for benign prostatic hyperplasia (BPH).

What does it do?

Gemtesa (Vibegron) works by relaxing the bladder muscle, allowing it to hold more urine. This may help reduce the urgency to urinate and decrease the frequency of urinary leaks or accidents.

How should I take it?

Gemtesa is taken orally once a day, and can be taken with or without food. If you're unable to swallow the tablet whole, you can crush it and mix it with 1 tablespoon of applesauce. Swallow the mixture immediately with a glass of water. Do not store the mixture for later use.

What if I missed a dose?

Take Gemtesa as soon as you remember, but if it's almost time for your next dose, skip the missed one. Do not take two doses at once.

What are the special precautions before taking Gemtesa?

Your doctor needs to know if you have any of the following conditions:

• Liver disease
• Prostate issues
• Kidney disease
• Difficulty passing urine

You may need to reduce your consumption of caffeinated sodas, tea, coffee, or alcohol, as these drinks can worsen your symptoms.

Consult your pediatrician before using this medicine in children, as special precautions may be necessary.

Does it have any side effects?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Gemtesa with any of the following medications:

Common side effects may include:
• Diarrhea
• Nausea
• Headache
• Urinary tract infection
• Upper respiratory tract infection

Serious side effects may include:
• Urinary retention: Gemtesa may increase the risk of not being able to empty your bladder, particularly if you have bladder outlet obstruction or are taking other medications for overactive bladder. Contact your doctor immediately if you're unable to empty your bladder.
• Angioedema: Gemtesa can cause an allergic reaction, leading to swelling of the face or throat, which may or may not cause breathing difficulties and can be life-threatening. If you experience any signs of angioedema or have trouble breathing, stop using Gemtesa and seek emergency medical help right away.

These are not all the possible side effects of Gemtesa. For more information, consult your doctor or pharmacist. If you have any concerns about side effects, contact your doctor for medical advice.

Is it safe to take it with another drug?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Inform your doctor about all the other medications you are taking, particularly:

• Digoxin or Digitalis

This is not a complete list. Other medications, including prescription and over-the-counter drugs, vitamins, and herbal supplements, may interact with Vibegron. Not all potential drug interactions are listed here.

How should I store it?
Store Gemtesa at room temperature, between 68°F and 77°F (20°C to 25°C). Dispose of any unused medicine safely.
What action should I take in case of overdose?
There is no reported adverse effects and if you believe you have taken an excessive amount of this medication, immediately contact your doctor or go to the nearest emergency room.
Is it safe for pregnant or breastfeeding women?

Gemtesa's effects on pregnancy are not fully known, and it is unclear whether it could harm an unborn baby. Inform your healthcare provider if you are pregnant or planning to become pregnant. Similarly, it is unknown if Gemtesa passes into breast milk.

Let your healthcare provider know if you are breastfeeding or planning to breastfeed, and they will guide you on whether it is safe to use Gemtesa while breastfeeding.

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