Why is Genvoya prescribed?

The combination drugs of elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide is a prescription drug used without other drugs for treatment of human immunodeficiency virus (HIV) infection, which causes acquired immune deficiency syndrome (AIDS). This medication is typically prescribed to individuals who have not yet been treated for HIV. This medication is available only with a doctor's prescription and comes in tablet form.

What does it do?

The combination of elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide helps inhibit the reproduction of the virus and may slow the damage to the immune system. This can help delay the onset of complications commonly associated with AIDS or HIV. However, it will not prevent the transmission of HIV to others, and those on this medication may still experience issues related to AIDS or HIV.

How should I use it?

Take this medication exactly as prescribed by your doctor. Do not take more of it, take it more frequently, or use it for a longer period than instructed. This medication should be taken with food.

Do not adjust the dose or discontinue use without first consulting your doctor. When you are nearing the end of your supply, contact your doctor or pharmacist in advance. Ensure that you do not run out of this medication.

The dosage of this medication can vary between patients weight. The information provided here includes only typical doses. If your prescribed dose differs, do not alter it unless directed by your doctor.

The amount of medicine you take will depend on its strength. The number of doses per day, the intervals between doses, and the duration of the treatment depend on the specific condition being treated.

What if I missed a dose?

You need to take this medication regularly to prevent drug resistance and if you miss a dose of this medication, take it immediately. Avoid taking a double dose to make up for the missed one.

What are the special precautions before using Genvoya?

Your doctor will need to monitor your progress with regular check-ups, particularly during the initial weeks of taking this medication. Blood and urine tests may be required to identify any potential side effects.

As you begin HIV treatment, your immune system may become stronger. Inform your doctor immediately if you notice any changes in your health. Your immune system might start addressing infections that were previously latent, such as pneumonia, herpes, or tuberculosis. Autoimmune conditions like Graves' disease, polymyositis, Guillain-Barré syndrome, and autoimmune hepatitis may also develop.

This medication does not reduce the risk of spreading HIV to others through sexual contact or contaminated blood. Ensure you practice safe sex, even if your partner is also HIV-positive, and avoid sharing needles.

Only take other medications, including prescription and over the counter (OTC) drugs, as well as herbal or vitamin supplements, if they have been approved by your doctor.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Most common reaction taking Genvoya is Nausea.

Contact your doctor immediately if you experience any of the following

Serious side effects may include:
• Acute renal failure
• Bloody urine
• Bone pain
• Dark urine
• Decreased appetite
• Difficulty breathing
• Reduced frequency or amount of urine
• Diarrhea
• Rapid, shallow breathing
• General discomfort
• Increased thirst
• Yellowing of the eyes and skin

Genvoya is not recommended for patients with severe renal and hepatic impairment.

Some side effects may not require medical attention and could diminish as your body adjusts to the medication. Your healthcare provider may offer advice on how to prevent or manage these effects.

Consult your healthcare professional if any of these less serious side effects persists.

Is it safe to use it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Genvoya with any of the following medications.

This medication should not be used in combination with the following drugs:

• Antiretroviral medications
• Apixaban
• Rivaroxaban
• Alfuzosin
• Benzodiazepines
• Carbamazepine
• Lamivudine
• Lomitapide
• Lovastatin
• Lurasidone
• Midazolam
• Phenobarbital
• Phenytoin
• Pimozide
• Rifampin
• Sildenafil
• Simvastatin
• St. John’s wort

Ask your doctor or pharmacist for other possible interactions not listed in this section.

How should I store it?

Store the medicine in a sealed container at below 30 °C (86 °F) room temperature, away from heat, moisture, and direct light. Keep this medication out of the reach of the children.

What action should I take in case of overdose?

There is no strong evidence of over dosage for Genvoya in patients. If it occurs monitoring of vital signs is necessary.

Is it safe for pregnant or breastfeeding women?

Genvoya is not recommended for use during pregnancy as it may not be effective for pregnant women. If you become pregnant or suspect you might be pregnant, inform your doctor immediately. At least one of the active ingredients in Genvoya can pass to your baby in your breast milk. Do not breastfeed if you are taking Genvoya.

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