Why is Glucotrol prescribed?

Glipizide is frequently prescribed to lower blood sugar levels in individuals with type 2 diabetes under drug class sulfonylurea.

Additionally, Glipizide might be used for other purposes as directed by your healthcare provider.

What does it do?

Glipizide works by improving your body’s insulin levels. Insulin, a hormone released by your pancreas, helps your body use blood sugar (glucose) for energy.

How should I use it?

Glipizide is currently available in 2.5mg, 5mg, and 10mg tablets and swallow the extended-release tablet whole; do not split, crush, or chew it. The maximum daily dose of Glipizide is 20mg.

Any dosage adjustment can be made based on the patient's glycemic level.

Follow the special meal plan provided by your doctor closely, as it is crucial for effectively managing your condition and ensuring the medication works properly. Additionally, be sure to exercise regularly and monitor your blood or urine sugar levels as directed.

Extended-release tablets:

Adults: Start with 5mg once daily with breakfast. Your doctor may adjust the dose, if necessary, but it usually does not exceed 20 mg per day and it is normal for part of the tablet to appear in your stool after the medicine has been absorbed by your body.

The dosage of this medication varies among patients. Follow your doctor's instructions.

What are the special precautions before using Glucotrol?

It is crucial for your doctor to monitor your progress through regular check-ups to ensure the medication is effective. Blood and urine tests may be required to detect any adverse effects.

Carefully follow all instructions from your healthcare team regarding:

• Drinking alcohol can cause severe low blood sugar.
• Family members should learn how to prevent or manage potential side effects. Additionally, patients may need special guidance on adjusting diabetes medication due to lifestyle changes.
• Carry your recent prescription during travel, account for time zone changes, and try to keep mealtimes consistent with your regular schedule.

Glipizide can cause hypoglycemia (low blood sugar), which may also result from delayed or missed meals, alcohol consumption, increased exercise, nausea or vomiting, interactions with other medications, or combined use with other diabetes medicines. Learn to recognize and treat low blood sugar symptoms to prevent serious complications.

Signs of low blood sugar include anxiety, being drunk, blurred vision, cold sweats, confusion, pale skin,shakiness, slurred speech, and unusual tiredness or weakness.

If you have low blood sugar symptoms, consume glucose tablets, gel, corn syrup, honey, sugar cubes, or drink fruit juice, regular soft drinks, or sugar dissolved in water.

Keep a glucagon kit and know how to use it and ensure that those around you are also familiar with its use.

Does it have any side effects?

While this medication provides necessary effects, it may also cause some unwanted side effects. Not all side effects will occur, but those that do may require medical attention.

Contact your doctor immediately if you experience any of the following side effects:
Common side effects may include:
• Blurred vision
• Tingling sensations
• Chills
• Coma
• Confusion
• Cool, pale skin
• Depression
• Impaired mobility
• Dizziness
• Fainting
• Rapid heartbeat
• Headache
• Increased hunger
• Joint pain
• Leg cramps
• Muscle aches or cramps
Serious side effects may include:
• Decreased interest in sex
• Dizziness or lightheadedness
• Excessive muscle tone
• Sensation of constant movement
• Flushing or redness of the skin
• Severe, throbbing headache
• Hives or welts
• Difficulty maintaining an erection
• Loss of sexual ability or desire
• Mood or mental changes
• Muscle stiffness
• Muscle tension or tightness
• Sensation of spinning
• Skin rash (encrusted, scaly, oozing)
• Sleepiness or unusual drowsiness

Is it safe to use it with another drug?

Specifically, discuss with your provider if you are using any of the following before starting glipizide:
• Fuconazole (Diflucan) and miconazole (Oravig)
• Colesevelam (Welchol)
• Clonidine
• Corticosteroids
• ACE inhibitors
• Antipsychotics (e.g., olanzapine & clozapine)
• Angiotensin receptor blockers (ARBs)

Ask your doctor or pharmacist for other possible interactions not listed in this section.

How should I store it?

Store the medication in a tightly sealed container at room temperature, keeping it away from heat, moisture, and direct sunlight

What action should I take in case of overdose?

During pregnancy, it is unclear whether glipizide could impact pregnancy or pose a risk to an unborn baby. Inform your healthcare provider if you are pregnant or planning to become pregnant.

It is not known if Glipizide is present in breast milk. Notify your healthcare provider if you are breastfeeding or intend to breastfeed.

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