Why is Indocin prescribed?

Indomethacin (Indocin) is being prescribed in combination with other drugs for the management of arthritis, gout and bursa sac that causes pain, swelling, inflammation, and stiffness of the joint muscles.

What does it do?

Indomethacin, classified under Non-steroidal Anti-inflammatory Drugs (NSAIDs), produces properties such as analgesic and anti-inflammatory effects that primarily works by inhibiting the enzyme called Prostaglandin that is responsible for pain sensation and inflammation; thus, reduce swelling and pain.

How should I take it?

Indocin is available as 50mg capsule that is intended for oral administration as a whole, not to be crushed or chewed, and should be taken with food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before taking Indocin?

Before taking Indomethacin, tell your doctor or pharmacist if you have any allergies to food and to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had bleeding problems, clotting problems, heart disease, nasal polyps, liver disease, stroke, intestinal problems and kidney disease.

Always take the drug with food. Avoid drinking alcohol as this may cause dizziness, drowsiness and stomach bleeding and can add to the effects of Indomethacin.

Avoid too much exposure in the sun as this may cause sunburned and skin blisters. Wear protective clothing and use sunscreen when outdoors.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Indomethacin, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Abdominal pain
• Constipation
• Diarrhea
• Dizziness
• Drowsiness
• Headache
• Increased blood pressure
• Itching
• Heartburn
• Nausea
• Sweating

Serious side effects may include:
• Black stool
• Bone marrow depression
• Chest pain
• Coughing of blood
• Dark urine
• Dysphagia
• Dyspnea
• Hallucinations
• Leukopenia
• Numbness
• Ringing of ears
• Slurred speech
• Yellowing of eyes and skin

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Indocin with any of the following medications:

• Advil
• Aleve
• Aldosterone
• Alfalfa
• Allopurinol
• Aliskiren
• Arthrotec
• Aspirin
• Betrixaban
• Captopril
• Celebrex
• Coumadin
• Diovan
• Enoxaparin
• Flector
• Fosinopril
• Furosemide
• Jantoven
• Ketorolac
• Lasix
• Lifezar
• Losartan
• Mobic
• Naproxen
• Pennsaid
• Pradaxa
• Symmetrel
• Tacrolimus
• Zestril

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Indomethacin in room temperature (25 °C) in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Do not open the capsule. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are no well-controlled studies and data regarding the safety of Indomethacin to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. The use of Indomethacin in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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