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Why is Invega prescribed?

Invega (Paliperidone) prescribed for the treatment of specific mental health conditions, including schizophrenia and schizoaffective disorder. Paliperidone is part of a group of medications known as atypical antipsychotics.

What does it do?

Invega helps restore the balance of certain natural chemicals in the brain.

How should I take it?

Take this medication orally, with or without food, as prescribed by your doctor, typically once a day. Swallow the tablets whole with water; do not crush or chew them, as this can cause the entire dose to be released at once, raising the risk of side effects. Your dosage will depend on factors such as your age, medical condition, and response to treatment.

What if I missed a dose?

If you miss to take Invega, take it as soon as you remember. However, if your next dose is approaching, skip the missed dose. Avoid taking two doses at once.

What are the special precautions before taking Invega?

Do not use Invega if you are allergic to paliperidone or risperidone (Risperdal). Paliperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this condition.

Using high doses or taking paliperidone long-term can lead to a serious, potentially irreversible movement disorder. The risk of developing this disorder increases with prolonged use, particularly in women or older adults.

To ensure Invega is safe for you, inform your doctor if you have a history of any of the following:

• Breast cancer
• Heart conditions or a previous heart attack
• Long QT syndrome (in yourself or a family member)
• High or low blood pressure, or episodes of fainting
• Low white blood cell (WBC) count
• Severe neurological reactions to antipsychotic medications
• Uncontrolled facial muscle movements
• Stomach or intestinal disorders
• Liver or kidney disease
• Electrolyte imbalances
• Diabetes (paliperidone may raise blood sugar levels)
• Seizures or epilepsy

If you are pregnant or planning to become pregnant while taking this medication, notify your doctor. Using antipsychotic medication during the last trimester of pregnancy can cause breathing or feeding difficulties, or withdrawal symptoms in newborns. However, stopping your medication abruptly during pregnancy may also lead to withdrawal symptoms or other complications. If you become pregnant, contact your doctor immediately. Do not discontinue Invega without medical guidance.

Does it have any side effects?

ISeek emergency medical assistance if you experience signs of an allergic reaction to Invega, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

• Tremors or shaking in your arms or legs
• Uncontrolled facial muscle movements (such as chewing, lip smacking, frowning, tongue movements, or eye blinking
• Any new or unusual involuntary muscle movements

Call your doctor right away if you experience any of the following:

• Breast swelling (in men or women) or nipple discharge
• Changes in menstrual cycles
• Impotence or a painful, prolonged erection lasting 4 hours or more
• Significant weight gain
• Low white blood cell count, causing symptoms like fever, chills, mouth or skin sores, sore throat, cough, or difficulty breathing
• High blood sugar, which may present as increased thirst, frequent urination, hunger, or a fruity breath odor
• Rapid or pounding heartbeat, chest fluttering, shortness of breath, or sudden dizziness, as if you might faint
• Severe nervous system reaction, including very stiff muscles, high fever, rapid heartbeat, and fainting
Common side effects may include:
• Anxiety
• Drowsiness
• Muscle stiffness, tremors, or shaking
• Uncontrolled movements, difficulty with walking, balance, or speech
• Weight gain
• Upset stomach or constipation
• Rapid heart rate
• Stuffy nose or sore throat
This is not a complete list of side effects. For further advice or concerns about side effects, contact your doctor.
Is it safe to take it with another drug?
Drug interactions can alter the effectiveness of your medications or increase the risk of serious side effects. This information does not cover all possible interactions. Maintain a list of all products you use, including prescription and over-the-counter medications, as well as herbal supplements, and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medication without your doctor’s approval.
• Bromocriptine
• Carbamazepine
• Levodopa
• Pramipexole
• Ropinirole
• Propranolol
• Chlorpromazine
• Asenapine
• Quetiapine
• Thioridazine
Always consult your doctor or pharmacist for detailed guidance about potential interactions with paliperidone.
How should I store it?
Store at room temperature, protected from light and moisture. Ensure all medications are kept out of reach of children and pets.
What action should I take in case of overdose?
Symptoms of an overdose may include extreme drowsiness, rapid heartbeat, and fainting. Seek immediate medical attention or visit the nearest emergency department.
Is it safe for pregnant or breastfeeding women?

Using anti-psychotic medicine during the last trimester of pregnancy may lead to breathing or feeding difficulties or withdrawal symptoms in the newborn. Inform your doctor if you are pregnant or planning to become pregnant while taking this medication.

Breastfeeding while using this medication may not be safe. Consult your doctor to understand any potential risks.

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