Why is Isordil prescribed?

Isosorbide dinitrate (Isordil) is prescribed for the treatment of certain heart problems such as angina, congestive heart failure and coronary artery disease.

What does it do?

Isosorbide dinitrate, belongs to a class of drugs called nitrates. It is an anti-hypertensive agent that primarily works by dilating the peripheral veins resulting to a decrease in workload of the heart and by relaxation of the vascular smooth muscle; thus, helping the blood flow smoothly.

How should I take it?

Isordil and its generic equivalents are available as 5mg, 10mg, 20mg and 30mg tablets. It is intended for oral administration as a whole, not to be crushed or chewed, and should be taken with or without food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Isordil?

Before taking Isosorbide dinitrate, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had anemia, low blood pressure, head injury, dehydration, stroke, cardiomyopathy and myocardial infarction.

Avoid drinking alcohol as this may cause dizziness and drowsiness and can add to the effects of Isosorbide dinitrate.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Isosorbide dinitrate, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Dizziness
• Drowsiness
• Fatigue
• Headache
• Light-headedness
• Nausea
• Redness of skin
• Tingling
• Weakness

Serious side effects may include:
• Blurred vision
• Dyspnea
• Methemoglobinemia
• Drowsiness
• Pale skin
• Rash
• Syncope
• Tachycardia
• Urticaria
• Unstable angina

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Isordil with any of the following medications:

• Abacavir
• Acarbose
• Acetazolamide
• Ampicillin
• Amvasc
• Avanafil
• Benazepril
• Biaxin
• Capomed
• Chloramphenicol
• Conivapan
• Coumadin
• Dapsone
• Diamox
• Elagolix
• Ergotamine
• Iloperidone
• Indinavir
• Jantoven
• Lopinavir
• Maraviroc
• Nizoral
• Norvasc
• Serzone
• Sporanox
• Triazolam
• Troglitazone
• Vardenafil
• Viagra
• Warfarin
• Zinc citrate

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Isordil at room temperature (25 °C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant from the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Isosorbide dinitrate to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.

The presence of Isosorbide dinitrate in human milk is still unknown. Consult your doctor before breastfeeding.

The use of Isosorbide dinitrate in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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