Why is Janumet prescribed?

Janumet is a drug combination of Sitagliptin and Metformin. Together with a healthy diet and regular exercise, it is prescribed to control the blood sugar of diabetic patients (specifically Type 2 Diabetes Mellitus). It is important to note that this medication is not effective for patients with Type 1 DM or Diabetic Ketoacidosis.

What does it do?

Blood sugar monitoring and maintenance should be the main concern of diabetic patients. Although with varying mechanisms, both Sitagliptin and Metformin, work synergistically in controlling a patient’s glycemic index. However, regular exercise and a healthy and well-balanced diet will aid in the patient’s condition.

How should I take it?

Janumet is currently available as Sitagliptin/Metformin with doses 50mg/500mg and 50mg/1000mg. It is also available as Janumet XR (Sitagliptin/Metformin), an extended-release tablet with doses 100mg/1000mg, 50mg/500mg and 50/1000mg. Each tablet should be taken as a whole (do not split) by mouth with food to avoid getting stomach upset. It is highly recommended to continue taking Janumet even if you have regulated your blood sugar within normal limits. Diabetes may be a lifetime condition, but a well-balanced diet, regular exercise and regular intake of your medications would make it manageable.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Do not take two doses just to make up for your missed dose.

What are the special precautions before taking Janumet?

Inform your doctor about all the medications you are taking, your current and previous medical history especially if you are an alcoholic or have problems with your heart, kidney, pancreas, or liver and if you have any allergies to Sitagliptin or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Janumet, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Headache
• Diarrhea
• Nausea
• Sore throat
• Joint pain

Serious side effects may include:
• Extreme weakness
• Tremors
• Fast or irregular heartbeats
• Rashes
• Swelling of the hands or legs
• Difficulty of breathing
• Seizure

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Janumet with any of the following medications:

• Alcohol
• Amaryl
• Diabeta
• Diamox
• Dichlorphenamide
• Dolutegravir
• Glucophage
• Glibenclamide
• Glimepiride
• Glipizide
• Glumetza
• Isoniazid
• Januvia
• Lanoxin
• Metaglip
• Norvasc
• Ranolazine
• Rosiglitazone
• Tagamet
• Tolbutamide
• Vandetanib
• Zonisamide

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Janumet in a tight container in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

The data on Janumet’s safety and efficacy in pregnant women as well as its presence in milk or its effects in breastfed infants have not been established. It should be noted that uncontrolled diabetes may pose a significant risk to pregnant women and their unborn children.

Inform your doctor if you are pregnant or breastfeeding or planning on doing so to ensure that the benefits of taking the medication outweigh the risks.

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