Why is Januvia prescribed?

Sitagliptin (Januvia) is a blood sugar controlling medication that is used as adjunct, along with a healthy diet and regular exercise, in patients with Diabetes Mellitus (DM) specifically Type 2. It should not be used in patients with Type 1 DM or Diabetic Ketoacidosis since it is not effective for these conditions.

What does it do?

Type 2 Diabetes Mellitus is a lifestyle condition in which patients are having difficulties regulating the blood sugar in their bodies caused by various mechanisms. Januvia belongs to a class called DPP-4 inhibitors that works by increasing and prolonging the levels of a certain hormone in the body which regulates the glucose concentrations in the blood. Regular exercise and a healthy and balanced diet together with Januvia will help improve the patient's condition.

How should I take it?

Januvia is currently available in 25mg, 50mg, and 100mg tablets. Each tablet should be taken as a whole (do not split) by mouth with or without food. It is important to note that Diabetes is a lifetime condition but is manageable. Regular intake of Januvia will help regulate your blood sugar hence, even if you feel that you are healthy, do not stop taking the medication unless advised by your doctor.

The dosage strength depends on every patient’s condition and the doctor’ prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Januvia?

Inform your doctor about all the medications you are taking, your current and previous medical history especially if you have problems with your heart, pancreas, or liver and if you have any allergies to Sitagliptin or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Januvia, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Headache
• Diarrhea
• Nausea
• Muscle or back pain
• Indigestion

Serious side effects may include:
• Gum bleeding
• Reddish, pinkish or brownish urine
• Heavy menstruation
• Rashes
• Difficulty of breathing
• Wheezing

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Januvia with any of the following medications:

• Biaxin
• Carbatrol
• Celexa
• Cymbalta
• Diabeta
• Dilantin
• Effexor
• Glimepiride
• Glipizide
• Heparin
• Ketoconazole
• Lasix
• Lexapro
• Lisinopril
• Paxil
• Pristiq
• Prozac
• Rifampin
• Ritonavir
• Sporanox
• St. John’s Wort
• Synthroid
• Tegretol
• Warfarin
• Zoloft

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Januvia in a tight container in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

At present, there is limited information regarding drug-related risks for major birth defects and miscarriage on pregnant women taking Januvia. However, poorly controlled Diabetes has risks to the mother and fetus.

There is still no sufficient scientific evidence regarding the presence of Sitagliptin in milk or its effects in breastfed infants.

Inform your doctor if you are pregnant or breastfeeding or planning on doing so to ensure that the benefits of taking the medication outweigh the risks.

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