Why is Lescol XL prescribed?

Lescol, with the generic name Fluvastatin, is prescribed to reduce the risk for developing complications (heart attack or stroke) of heart disease and decrease the need for surgery. It is also prescribed, together with diet, exercise, and weight-loss, to lower the levels of low-density lipoprotein/LDL (a.k.a. “bad” cholesterol) and increase the levels of high-density lipoprotein/HDL (a.k.a. “good” cholesterol) in the blood in adults. It is also prescribed to children aged 10-17 years who are diagnosed with familial heterozygous hypercholesterolemia, a genetic disorder of cholesterol metabolism which predisposes one to develop heart disease.

What does it do?

Fluvastatin belongs to a class of medications called HMG-COA reductase inhibitors that works by slowing the production of cholesterol in the body to prevent build up in the walls of arteries, heart, and brain, to prevent heart disease, heart attacks, and stroke.

How should I take it?

Lescol is currently available as 20mg and 40mg capsules (Lescol) and 80mg extended-release tablets (Lescol XL) taken whole (not split, chewed, or crushed) by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Lescol XL?

Eat a low-fat, low-cholesterol diet, and follow dietary and exercise recommendations given by your doctor.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Lescol, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Lescol XL, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Confusion
• Bowel movement changes (diarrhea or constipation)
• Memory loss
• Back pain
• Headache
• Heartburn
• Sinus pain

Serious side effects may include:
• Itching, hives, or rash
• Muscle pain or weakness
• Fever
• Fatigue
• Changes in appetite
• Fatigue
• Abdominal pain
• Changes in the color of urine
• Yellowish discoloration of the skin or eyes
• Flu-like symptoms

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Lescol with any of the following medications:

• Adalimumab
• Black cohosh
• Bosentan
• Cannabidiol
• Ceritinib
• Clofibrate
• Colchicine
• Cordarone
• Coumadin
• Daptomycin
• Delavirdine
• Erythromycin
• Gemfibrozil
• Hydralazine
• Interferon-alfa
• Isoniazid
• Lanoxin
• Leflunomide
• Lenalidomide
• Lipitor
• Lofibra
• Lopitamide
• Mibefradil
• Mipomersen
• Niacin
• Oxaliplatin
• Paclitaxel
• Pexidartinib
• Prograf
• Rapamune
• Remdicivir
• Restasis
• Vfend
• Zafirlukast
• Zidovudine

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Lescol in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Fluvastatin is contraindicated for use in pregnant women, women trying to get pregnant, or are breastfeeding. Hence, the potential risks and benefits of using Lescol in pregnant or breastfeeding infants should be carefully considered.

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