Why is Levaquin prescribed?

Levofloxacin (Levaquin) is prescribed alone or in combination with other medications for the treatment of bacterial infections such as skin infection, sinuses, lungs and ears. It is also used in treating urinary infections.

What does it do?

Levofloxacin, a fluoroquinolone, is an anti-bacterial drug that primarily works by inhibiting topoisomerase IV and the DNA gyrase, both of which are responsible for DNA replication; thus, preventing the reproduction of bacterial growth.

How should I take it?

Levaquin and its generic equivalents are available as 250mg, 500mg and 750mg tablets. It is intended for oral administration as a whole, not to be crushed or chewed, and should be taken once daily with or without food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before taking Levaquin?

Before taking Levofloxacin, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had diabetes, joint problems, tendon problems, kidney problems, depression, myasthenia gravis, peripheral neuropathy, aneurysm, high blood pressure, Marfan syndrome and Ehlers-Danlos syndrome.

Avoid drinking alcohol as this may cause dizziness and drowsiness and can add to the effects of Levofloxacin.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Levaquin, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Abdominal pain
• Chills
• Diarrhea
• Fatigue
• Headache
• Insomnia
• Itching
• Nausea
• Rash
• Vomiting

Serious side effects may include:
• Agitation
• Central nervous system effects
• Clostridium difficile-associated diarrhea
• Dark urine
• Dysrhythmia
• Hallucinations
• Liver dysfunction
• Paranoia
• Peripheral neuropathy
• Seizures
• Sensitivity to the sun
• Tendon rupture

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Levofloxacin with any of the following medications:

• Acarbose
• Alfuzosin
• Anafranil
• Asendin
• Betapace
• Biaxin
• Cataflam
• Celebrex
• Chlorpromazine
• Cordarone
• Diprolene
• Disopyramide
• Droperidol
• Elavil
• Estraderm
• Glumetza
• Iron sucrose
• Lanoxin
• Fosamax
• Isoniazid
• Lanoxin
• Lexapro
• Lozol
• Luvox
• Ondansetron
• Pentamidine
• Procainamide
• Quinidine
• Retin-A
• Saquinavir

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Levofloxacin in room temperature (25 °C) in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Levofloxacin to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. However, as per USA FDA, Levofloxacin is categorized as Pregnancy Category C which states that no potential harm and well-controlled studies done in humans, but animal studies have shown adverse effects on the fetus.

Limited studies have shown the presence of Levofloxacin in human milk. Consult your doctor before breastfeeding.

The use of Levofloxacin in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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