NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Locoid prescribed?

Hydrocortisone butyrate (Locoid) cream is prescribed for the treatment of redness, itchiness, and swelling of skin conditions that are treatable with steroid medications such as eczema and psoriasis.

What does it do?

Eczema is a condition where the skin becomes dry and extremely itchy and may develop red and inflamed patches. Psoriasis is a condition where the skin becomes itchy and it may sting or burn, and it makes the skin look more inflamed. Locoid belongs to a drug class called corticosteroids and it works by stimulating the release of substances found in the skin to relieve redness, itching, and swelling.

How should I apply it?

Locoid and its generic equivalents are currently available as a 0.1% cream. It should only be applied to the skin. Avoid getting Locoid cream into your eyes or mouth.

Wash your hands thoroughly before and after (except when you are treating a hand condition) handling the medication. Apply a small amount to the area to be treated and rub it in carefully. Do not use any coverings, bandages, or wraps to cover the area unless directed by your doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if used properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, apply it immediately and adjust the time of your next dose depending on your doctor’s advice. Never apply two doses at the same time just to make up for your missed dose.

What are the special precautions before applying Locoid?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Locoid or any other ingredients included in the manufacture of this medication.

Locoid should not be used by children younger than 2 years of age unless directed by your doctor.

For the drug label information of Locoid, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Burning sensation
• Itching
• Redness
• Skin discoloration
• Skin dryness
• Small red or white skin bumps

Serious side effects include:
• Diarrhea
• Increased body hair growth
• Muscle weakness
• Nausea
• Severe irritation
• Severe rashes
• Slow wound healing
• Swelling
• Weight gain

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are using Locoid with any of the following medications:

• Acarbose
• Acetohexamide
• Actos
• Albiglutide
• Amaryl
• Avandamet
• Canagliflozin
• Chlorpropamide
• Coumadin
• Dapagliflozin
• Diabeta
• Dulaglutide
• Dulera
• Ertugliflozin
• Exenatide
• Glucophage
• Insulin aspart
• Insulin detemir
• Insulin glargine
• Insulin lispro
• Insulin regular
• Janumet
• Jardiance
• Liraglutide
• Lixisenatide
• Metaglip
• Mifepristone
• Miglitol
• Nesina
• Norepinephrine
• Oxycodone
• Prograf
• Rituximab
• Saxagliptin
• Semaglutide
• Sirolimus
• Starlix
• Sulfadiazine
• Tolazamide
• Tolbutamide
• Tradjenta
• Troglitazone
• Vindesine
• Voglibose
• Xarelto
• Zolpidem

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Locoid in its container in a clean environment away from excessive heat and moisture.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Present data suggest that the use of Locoid in pregnant women has not established its developmental risks.

There is also limited data on the presence of Locoid in human milk or its effects on the breastfed infant.

The use of Locoid in pregnant and breastfeeding women should be carefully considered to evaluate if its potential benefits outweigh the risks.

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