Why is Lopid prescribed?

Gemfibrozil (Lopid) is being prescribed in combination with a proper and healthy diet to reduce elevated cholesterol and triglycerides in the blood caused by a poor eating lifestyle.

What does it do?

Occasional consumption of red meat products, full-fat dairy goods such as cheese, milk, and yogurt, and animal fats like butter, margarine, and spreads may cause several illnesses like heart disease due to poor diet associated with hypercholesterolemia and dyslipidemia. Patients with high levels of cholesterol and fats in the blood are treated with anti-lipidemic agents such as Gemfibrozil.

Gemfibrozil, a fibric acid derivative, works by increasing the lipoprotein lipase enzyme and the production of apoprotein C-III, thus, breaking down unnecessary fats in the blood.

How should I take it?

Lopid is available as a 600mg tablet that is intended for oral administration as a whole, not to be crushed or chewed, and should be taken 30 minutes before a meal as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before taking Lopid?

Before taking Gemfibrozil, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had kidney disease, gallbladder disease, hepatitis, cirrhosis, liver disease, and gallstones.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Lopid, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Abdominal pain
• Decreased libido
• Diarrhea
• Dizziness
• Drowsiness
• Impotence
• Indigestion
• Joint pain
• Muscle pain
• Numbness
• Vision problems

Serious side effects may include:
• Dark urine
• Dyspnea
• Dysrhythmia
• Hallucinations
• Hives
• Jaundice
• Kidney failure
• Myopathy
• Pain when urinating
• Rhabdomyolysis
• Swelling of the face and tongue
• Synovitis

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Lopid with any of the following medications:

• Amaryl
• Belinostat
• Caduet
• Cataflam
• Cholestyramine
• Cilostazol
• Colchicine
• Colestipol
• Coumadin
• Crestor
• Diabeta
• Diclofenac
• Diovan
• Elagolix
• Fluvastatin
• Imodium
• Irinotecan
• Lescol
• Lipitor
• Livalo
• Metaglip
• Mevacor
• Pioglitazone
• Pitavastatin
• Pravachol
• Pravaz
• Repaglinide
• Singulair
• Voltaren
• Zocor

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Lopid at room temperature (25 °C) in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant from the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications. 

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Gemfibrozil to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. However, as per US FDA, Gemfibrozil is categorized as Pregnancy Category C which states that no potential harm and well-controlled studies have been done in humans; but animal studies have shown adverse effects on the fetus.

The presence of Gemfibrozil in human milk is still unknown. Consult your doctor before breastfeeding.

The use of Gemfibrozil in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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