NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Mexitil prescribed?

Mexitil (Mexiletine) is typically used to treat abnormal heart rhythms that occur in the lower chambers of the heart, known as the ventricles. This condition is called ventricular arrhythmia. Mexiletine is intended only for individuals with serious cases of this condition.

What does it do?

Mexiletine works by blocking specific nerve signals in the heart, helping to slow down abnormal rhythms in the ventricles and restore a normal heart rhythm.

How should I take it?

Take Mexiletine exactly as prescribed usually 200mg every 8 hours. Your doctor may adjust the dose to ensure the best results. To reduce stomach irritation, take Mexiletine with food or an antacid.

What if I missed a dose?

Avoid skipping doses, changing your schedule, or stopping Mexiletine without your doctor's advice, as this could worsen your condition.

What are the special precautions before taking Mexitil?

Do not use Mexiletine if you are allergic to it or have a serious heart condition like AV block, unless you have a pacemaker.

Before using Mexiletine, inform your doctor if you have the following conditions:

• A weakened immune system
• Liver disease
• Epilepsy or seizures
• Congestive heart failure
• Or if you have recently taken other heart rhythm medications such as Lidocaine or Quinidine.

Mexiletine may also cause abnormal liver function tests, particularly in people with congestive heart failure or circulation problems.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Serious side effects may include:
• A new or worsening irregular heartbeat
• Chest pain
• Signs of liver issues such as upper stomach pain, dark urine, pale stools, or yellowing of the skin or eyes (jaundice)

Common side effects may include:
• Blurred vision
• Heartburn
• Difficulty with coordination
• Dizziness or lightheadedness
• Tremors or nervousness

This is not a complete list of side effects. Contact your doctor for medical advice regarding any side effects.

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Mexitil with any of the following medications:

Before using mexiletine, be sure to inform your healthcare provider if you are taking any of the following:

• Rifampin, often used to treat infections
• Cimetidine, typically used for heartburn
• Theophylline, used to manage lung diseases
• Fluvoxamine, commonly prescribed for depression
• Propafenone, used to treat abnormal heart rhythms (arrhythmia)
• Products containing caffeine, which may be found in wakefulness aids, diuretics, headache remedies, or hangover treatments
• Phenytoin (Dilantin and others) or Phenobarbital, which are used to control seizures

Other medications may also affect the blood levels of Mexiletine, and Mexiletine may affect how other drugs work. Always provide your doctor with a complete list of all medications you are currently taking or have recently used.

How should I store it?

Store Mexitil in its original container with the lid tightly closed at room temperature (20 C to 25 C). Keep it out of reach of children, and maintain at room temperature away from excessive heat and moisture.

What action should I take in case of overdose?

In case of overdose, seek emergency help. Symptoms may include unconsciousness, dizziness, seizures, and irregular heartbeat.

Is it safe for pregnant or breastfeeding women?

Mexiletine’s safety during pregnancy is unclear but based on test it appears with breastfeeding. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding to assess the risks and benefits before using this medication.

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