Why is Mezavant prescribed?

Mezavant, with generic name Mesalamine, is prescribed to people diagnosed with ulcerative colitis. Ulcerative colitis is a condition where there is irritation, swelling, and ulcers in the lining of the large intestine (colon) and rectum.

What does it do?

Mesalamine is an anti-inflammatory agent that reduces the inflammation of the lining of the large intestines and rectum, controlling the symptoms such as recurrent abdominal pain, diarrhea, rectal pain, and bleeding.

How should I take it?

Mezavant is currently available as a 1200mg tablet and as Mezavant XL, an extended-release tablet (Mezavant XL) taken whole (not split, chewed, or crushed) by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Mezavant?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Mezavant or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Mezavant, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Muscle pain, spasm, or stiffness
• Back pain
• Nausea
• Flatulence
• Bowel changes
• Dizziness
• Sweating
• Acne
• Hair loss
• Vomiting
• Appetite changes

Serious side effects include:
• Itching, hives or rash without fever
• Difficulty of breathing
• Bloody, black, or coffee-ground vomitus
• Blood or tar-like stools
• Chest pain

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Mezavant with any of the following medications:

• Adefovir
• Advil
• Bacitracin
• Botulism immunoglobulin
• Cataflam
• Celebrex
• Cidofovir
• Coumadin
• Cytomegalovirus immunoglobulin
• Deferasirox
• Diatrizoate
• Etidronate
• Foscarnet
• Gentamicin
• Glimepiride
• Iopamide
• Iodipamide
• Iodixanol
• Iohexol
• Iopamidol
• Iopromide
• Iothalamate
• Ioxaglate
• Ioxilan
• Intravenous or subcutaneous immunoglobulin
• Kanamycin
• Ketoprofen
• Ketorolac
• Lithium
• Mefenamic acid
• Methotrexate
• Metrizamide
• Naproxen
• Oxaliplatin
• Piroxicam
• Prograf
• Rapamune
• RSV immunoglobulin
• Rho (d) immunoglobulin
• Streptomycin
• Tobradex
• Tolbutamide
• Vancomycin
• Varicella vaccine
• Voltaren
• Zoledronic acid

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Mezavant in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Mesalamine is acceptable for use if needed in pregnant women, women trying to get pregnant, and breastfeeding women. Plasma drug levels should be monitored regularly throughout pregnancy until the postpartum period. Immediately inform your doctor if you are pregnant or planning to get pregnant to check if you can take the medication or not.

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