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Why is Monopril prescribed?

Monopril (Fosinopril Sodium) is an ACE inhibitor (angiotensin-converting enzyme inhibitor) primarily to treat high blood pressure (hypertension) and congestive heart failure. This medication may be prescribed for other conditions as directed by your healthcare provider.

What does it do?

Monopril (Fosinopril Sodium) inhibits the enzyme that creates angiotensin II, a hormone that causes blood vessels to tighten. By blocking this hormone, blood vessels relax, improving blood flow. This medicine helps the heart function more efficiently, lowers blood pressure, and may decrease the risk of heart attacks and strokes.

How should I take it?

The usual starting dose for adults is 10 mg once a day. Depending on your condition and response to the medication, your doctor may adjust the dose, which can range from 20 to 40 mg daily, and in some cases, up to 80 mg daily.

It's important to follow your doctor's instructions and not to change your dose or stop taking Monopril without consulting them.

What if I missed a dose?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue taking the next dose only. Avoid taking double or extra doses.

What are the special precautions before taking Monopril?

Before taking Monopril (Fosinopril Sodium), it's important to consider the following precautions:

• Inform your doctor if you have ever had an allergic reaction to Monopril (Fosinopril Sodium) or any other ACE inhibitors.
• Disclose any history of heart disease, recent heart attack, kidney disease, liver disease, or low blood pressure.
• Monopril is not recommended during pregnancy. If you become pregnant, stop taking Monopril and inform your doctor immediately.
• Avoid taking fosinopril within 36 hours before or after taking any medication that contains sacubitril (such as Entresto).
• Let your doctor know about all medications you are taking, especially diuretics, NSAIDs and medications for organ transplant rejection.

It's crucial to have a thorough discussion with your healthcare provider to ensure that Monopril is safe and appropriate for you.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Dry cough
• Dizziness
• Headache
• Nausea and vomiting
• Fatigue
• Muscle or joint pain

Serious side effects may include:
• Difficulty in breathing
• Fainting
• Sudden vision loss or blurred vision
• Fast, slow, or irregular heartbeats
• High potassium levels (hyperkalemia)
• Severe headache
• Signs of allergic reaction

If you experience any of these side effects, especially the more serious ones, contact your healthcare provider and seek medical attention immediately.

Is it safe to take it with another drug?

Monopril can harm your kidneys, especially if used alongside certain medications for infection, cancer, or osteoporosis. Avoid taking antacids within 2 hours before or after taking Monopril.

Inform your doctor about all your other medications, particularly:

• Diuretics or "water pills" that may increase blood potassium such as spironolactone, triamterene, amiloride.
• Organ transplant rejection prevention drugs such as temsirolimus, sirolimus, everolimus.
• NSAIDs (Nonsteroidal Anti-inflammatory Drugs) such as aspirin, ibuprofen, naproxen.
• Heart or blood pressure medications.
This list is not complete. Other drugs, including over-the-counter medicines, vitamins, and herbal products, may also interact with Monopril.
How should I store it?
Store the medication at room temperature, between 68°F and 77°F (20°C and 25°C). It can be briefly exposed to temperatures between 59°F and 86°F (15°C and 30°C), such as during transport. Keep it in its original container to protect it from light and moisture, and out of reach of children and pets.
What action should I take in case of overdose?
In case of a Monopril (Fosinopril Sodium) overdose, it's crucial to seek medical attention immediately or go to the nearest hospital right away.
Is it safe for pregnant or breastfeeding women?

Monopril (Fosinopril Sodium) is generally not recommended for pregnant or breastfeeding women. Studies have shown potential risks to the fetus, including congenital malformations and neonatal complications1. Additionally, the drug can be excreted into breast milk, and its effects on nursing infants are unknown.

If you're pregnant or breastfeeding and taking Monopril, it's important to consult your healthcare provider for alternative treatments.

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