NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Monovisc prescribed?

Monovisc (Sodium Hyaluronate) is prescribed to treat knee pain caused by osteoarthritis. This can help improve joint function and provide pain relief for individuals who haven't responded well to other treatments.

What does it do?

Monovisc is made from ultra-pure hyaluronic acid, a key component of the synovial fluid in a healthy knee. It functions as a lubricant and shock absorber in the knee joint, allowing for smooth movement, similar to the body's natural hyaluronan.

What does it do?

For adults age 21 years and older, Monovisc (Sodium Hyaluronate) is administered as a single intra-articular injection directly into the knee joint. Your doctor will administer a single injection of Monovisc (88 mg/4 mL) into your knee. If treatment is needed for both knees, use a separate syringe for each knee.

What if I missed a dose?

Since Monovisc (Sodium Hyaluronate) is administered as a single injection by a healthcare provider, it doesn't need a daily dosing schedule. If you need more than one Monovisc injection, contact your doctor for further instructions.

What are the special precautions before taking Monovisc?

Before taking Monovisc (Sodium Hyaluronate), it's important to consult with your doctor or healthcare provider to ensure its suitability for your condition. Here are some special precautions to keep in mind:

• Inform your healthcare professional of any known allergies before receiving Monovisc.
• Monovisc should only be administered by a qualified physician or a properly licensed practitioner.
• The safety and effectiveness of Monovisc in joints other than the knee have not been established in U.S. studies.
• Inform your healthcare professional if you are pregnant or nursing, as the safety and effectiveness of Monovisc during these periods have not been demonstrated.
• The sterile, pre-filled syringe is intended for single use only and should be used immediately after opening, with any unused Monovisc discarded and not resterilized.
• Monovisc is not authorized for use in individuals under the age of 21.

You should not use Monovisc if:

• The packaging has been opened or damaged.
• If you have an infection in your knee or the surrounding skin.
• If you have bleeding or blood clotting disorders.

It’s important to always follow your healthcare provider's instructions and report any unusual symptoms or side effects immediately.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

The most frequently reported adverse events related to Monovisc include the following:

• Injection site reactions (pain, swelling, redness)
• Joint pain and swelling
• Headache
• Dizziness
• Chills
• Hives
• Itching
• Rash

These side effects are generally mild and temporary, but it's important to consult your healthcare provider if you experience any unusual or severe symptoms.

Also, if you experience any of the serious side effects, such as unusual bleeding or bruising, severe joint pain, or any signs of infection, seek medical attention immediately.

Is it safe to take it with another drug?

Here are some medications known to interact with Monovisc:

• Benzalkonium Chloride (topical)
• Cetylpyridinium (topical)
• COVID-19 mRNA Vaccines (Moderna, Pfizer)

Inform your doctor or healthcare providers about all the medicines you currently use, as well as any new medication you start or stop using.

How should I store it?

Monovisc (Sodium Hyaluronate) should be stored in its original package at room temperature, specifically below 77°F (25°C). It is important not to freeze the product and to ensure the packaging is intact and unopened until ready for use.

What action should I take in case of overdose?

Since Monovisc is administered by a healthcare professional in a medical setting, an overdose is unlikely to occur. However, if an overdose of Monovisc (Sodium Hyaluronate) does happen, it is crucial to seek immediate medical attention.

Is it safe for pregnant or breastfeeding women?

If you are pregnant or planning to become pregnant while using Monovisc, tell your doctor, as its safety for unborn babies has not been tested. Additionally, inform your doctor if you are breastfeeding, as it is not known whether hyaluronan passes into breast milk or if it could harm a nursing baby, and the safety and effectiveness of Monovisc in lactating women have not been tested.

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