MYFORTIC (Mycophenolic Acid)-FDA REMS
MYFORTIC (Mycophenolic Acid)
Buy MYFORTIC brand or generic Mycophenolic Acid prescription drug from Canada
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Why is Myfortic prescribed? Myfortic, also known as mycophenolic acid, is prescribed to prevent organ rejection in patients who have undergone a kidney transplant. It's an immunosuppressant, which means it weakens the immune system to stop it from damaging the new organ. What does it do? Myfortic (Mycophenolic Acid) targets the immune system by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH), which is crucial for producing guanine nucleotides—essential components of DNA and RNA. This inhibition specifically reduces lymphocyte proliferation, as these white blood cells rely heavily on the de novo synthesis pathway. Consequently, Myfortic suppresses the immune response, helping prevent organ rejection by reducing lymphocyte activity. How should I take it?Here are some general guidelines for taking Myfortic:
- The typical dose for adults is 720 mg twice daily, totaling 1,440 mg per day. For pediatric patients, the dose is based on body surface area (BSA).
- Take Myfortic on an empty stomach, either 1 or 2 hours after meals. This helps ensure proper absorption.
- Swallow the tablets whole with water. Do not crush, chew, or cut the tablets, as they have an enteric coating designed to protect your stomach.
- Take Myfortic at the same times each day to maintain steady levels in your body.
Always follow your doctor's specific instructions, as they may tailor the dosage to your individual needs.
What if I missed a dose? If you forget to take Myfortic, take it as soon as you remember. Then, take your next dose at its regular time. If it is almost time for your next dose, skip the missed dose. Do not take two doses at once. What are the special precautions before taking Myfortic?Before taking Myfortic (Mycophenolic acid), there are several important precautions to keep in mind:
- Tell your doctor about all other medications you are taking, as Myfortic can interact with other drugs.
- Do not take Myfortic if you are allergic to mycophenolic acid or any of the other ingredients in the medication
- Tell your doctor if you have a history of infections, especially viral infections like hepatitis B or C, as Myfortic can reactivate these infections.
- If you have had stomach ulcers or other severe digestive problems, discuss this with your doctor, as Myfortic can exacerbate these conditions.
- Inform your doctor if you have any rare hereditary enzyme deficiencies, such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome.
- Myfortic can increase the risk of certain cancers, including lymphoma. Regular monitoring and check-ups are essential.
- Myfortic can reduce your skin's ability to protect against the sun, so use sunscreen and avoid excessive sun exposure.
- Common side effects may include:
- Anemia
- Constipation
- Nausea
- Urinary tract infection
- Upset stomach
- Vomiting
- Diarrhea
- Viral infection
- Serious side effects may include:
- Swelling of the face, lips, tongue, or throat
- Severe infections, including fever, chills, flu-like symptoms, and mouth sores
- Signs of kidney issues, such as changes in urine output, or blood in urine
- Jaundice (yellowing of the skin or eyes)
- Cancer such as lymphoma and skin cancer
- Proton pump inhibitors (e.g., omeprazole, pantoprazole), antivirals (e.g., Valganciclovir)
- Certain antibiotics (e.g., Sulfamethoxazole/Trimethoprim)
- Blood pressure medications (e.g., Amlodipine, Lisinopril)
- Cholesterol-lowering drugs (e.g., Atorvastatin)
- Multivitamins and supplements (e.g., Folic acid, Vitamin B12)
Myfortic should not be taken with azathioprine or mycophenolate mofetil (MMF), as these drugs also affect purine metabolism and can increase the risk of adverse effects.
Always tell your healthcare provider about all the medications you are taking. They can help you manage potential interactions and adjust your treatment plan if necessary.
How should I store it? Keep Myfortic at room temperature, ideally between 20°C to 25°C (68°F to 77°F). Store Myfortic in its original container, away from direct light and moisture. What action should I take in case of overdose?In case of an overdose with Myfortic (Mycophenolic Acid), it's important to seek medical attention immediately. Contact emergency services or go to the nearest hospital right away. Overdose can lead to severe side effects, including oversuppression of the immune system, increased risk of infections, and blood dyscrasias (abnormalities in blood cells).
Is it safe for pregnant or breastfeeding women?Myfortic (Mycophenolic acid) is not recommended for pregnant women due to its potential to cause birth defects and miscarriages. If you are pregnant or planning to become pregnant, it's crucial to discuss alternative treatments with your doctor.
Regarding breastfeeding, it is uncertain if this drug passes into breast milk, but it may have adverse effects on a nursing infant. Breastfeeding is not recommended while using this medication and for 6 weeks after discontinuation.
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