Why is Namenda prescribed?

Memantine (Namenda) is prescribed for the treatment of loss of memory, problem-solving and other language and thinking skills that may lead to Alzheimer’s disease.

What does it do?

Memantine, an N-methyl-D-aspartate (NMDA) antagonist, primarily works by blocking the excitatory neurotransmitter such as glutamate, an amino acid responsible for sending signals in the cells which an excess excitation can lead to cell death; thus, reducing the action helps in the improvement of performance, ability and awareness of the body.

How should I take it?

Namenda and its generic equivalents are available 5mg and 10mg tablets. It is intended for oral administration as a whole, not to be crushed or chewed, and should be taken with or without food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before using Namenda?

Before taking Memantine, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had kidney disease, gallbladder disease, severe urinary tract infection, epilepsy, seizures and liver problems.

Avoid drinking alcohol as this may cause dizziness and drowsiness and can add to the effects of Memantine.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Namenda, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Abdominal pain
• Back pain
• Chills
• Constipation
• Cough
• Diarrhea
• Fatigue
• Headache
• Nausea

Serious side effects include:
• Acute renal failure
• Cerebral infarction
• Hepatitis
• Intracranial hemorrhage
• Leukopenia
• Liver failure
• Neuroleptic malignant syndrome
• Pancreatitis
• Steven-Johnson syndrome
• Suicide
• Swelling of hands and feet
• Urticaria

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Memantine with any of the following medications:

• Acetazolamide
• Aluminum hydroxide
• Cimetidine
• Cordarone
• Delsym
• Dextrometorphan
• Dyrenium
• Floxin
• Glucophage
• Isoptin SR
• Ketamine
• Lanoxin
• Metformin
• Methazolamide
• Methyclothiazide
• Midodrine
• Mirapex
• Potassium citrate
• Pramipexole
• Proamatine
• Procainamide
• Quinine sulphate
• Robitussin
• Sodium bicarbonate
• Sodium citrate
• Symmetrel
• Tagamet
• Triamterene
• Vandetanib
• Zonisamide

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Namenda in room temperature (25°C) in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Memantine to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. However, as per US FDA, Memantine is categorized as Pregnancy Category B which states that there is no potential risk shown in animals but there are also no available studies for human safety.

The presence of Memantine in human milk is still unknown. Consult your doctor first before breastfeeding.

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