Why is Neupro prescribed?

Rotigotine (Neupro) is prescribed for the treatment of the symptoms associated with Parkinson’s disease. It is also used for the treatment of a condition called restless legs syndrome (RLS).

What does it do?

Parkinson’s disease is due to low or inadequate levels of dopamine (a chemical substance in the brain) causing muscle stiffness, tremors, and balance problems. Restless legs syndrome is a condition that causes an unpleasant sensation in the legs, urging you to move them to ease the discomfort. Rotigotine is classified as a dopamine agonist that primarily works by acting similarly to dopamine, allowing your body to regain its normal movements.

How should I apply it?

Neupro and its generic equivalents are currently available as 2mg and 4mg patches. The patch should only be applied to the skin.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if used properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, apply it immediately and adjust the time of your next dose depending on your doctor’s advice. Never apply two doses at the same time just to make up for your missed dose.

What are the special precautions before applying Neupro?

Before applying Rotigotine, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had asthma, blood pressure problems, mental illness, heart disease, or a sleeping disorder.

Rotigotine may cause drowsiness. When getting up from a lying or sitting position, do it slowly and sit for a few minutes before standing up completely. Avoid drinking alcohol as this may also cause drowsiness which can add to the effects of Rotigotine.

If you will undergo medical procedures such as magnetic resonance imaging (MRI) or cardioversion, inform your doctor that you are using Rotigotine.

For the drug label information of Neupro, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Dizziness
• Headache
• Itching
• Nausea
• Redness
• Sleep problems
• Swelling
• Vision problems
• Vomiting

Serious side effects include:
• Confusion
• Extreme drowsiness
• Fast heart rate
• Feeling agitated
• Lightheadedness
• Severe irritation of the skin
• Unusual behaviors and thoughts

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are using Neupro with any of the following medications:

• Alfentanil
• Amisulpride
• Asendin
• Azatadine
• Baclofen
• Biperiden
• Bromocriptine
• Buspirone
• Butorphanol
• Carisoprodol
• Clemastine
• Comtan
• Cyclizine
• Dezocine
• Ezogabine
• Fibanserin
• Fluphenazine
• Halazepam
• Hydrocodone
• Imipramine
• Keppra
• Lamictal
• Latuda
• Lumateperone
• Meclizine
• Molindone
• Nabilone
• Neurontin
• Opicapone
• Orphenadrine
• Paxil
• Phenelzine
• Pregabalin
• Propoxyphene
• Risperdal
• Sabril
• Seroquel
• Skelaxin
• Sodium oxybate
• Sufentanil
• Tasmar
• Zaleplon
• Zyrtec

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Neupro at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Rotigotine to determine drug-associated risks of major maternal defects, miscarriages, and fetal outcomes.

Limited data have been established indicating the presence of Rotigotine in human milk. Consult your doctor first before breastfeeding.

The use of Rotigotine in pregnant and breastfeeding women should be carefully evaluated to determine if its potential benefits outweigh the risks.

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