Why is Nitoman prescribed?

Tetrabenazine (Nitoman) is prescribed for the management of chorea, a series of uncontrollable movements, which is associated by Huntington’s disease.

What does it do?

A patient suffering from Huntington’s disease, an autosomal disorder, primarily affects functional abilities such as body movements and cognitive thinking because the disease is said to cause progressive deterioration of nerve cells in the brain. Some medications for hyperkinetic movement disorders help in alleviating the symptoms of the disease and one of these is Tetrabenazine.

How should I take it?

Nitoman is available as 25mg scored tablet. It is intended for oral administration as a whole, not to be crushed or chewed, and should be taken in the morning with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

If your doctor specifies to take more than 50mg of Nitoman every day, a blood test is recommended.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

Note: If you missed dose for more than 5 days, taking another dose is not recommended until you talk to your healthcare provider.

What are the special precautions before using Nitoman?

Before taking Tetrabenazine, tell your doctor or pharmacist if you have any allergies to food and to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or had liver disease, suicide attempts, psychosis, breast cancer, unstable heart rate or a heart attack.

Avoid drinking alcohol as this may cause dizziness and drowsiness and can add to the effects of Tetrabenazine.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Nitoman, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Agitation
• Anxiety
• Depression
• Fatigue
• Insomnia
• Nausea
• Restlessness
• Sedation

Serious side effects include:
• Hoarseness and difficulty breathing or swallowing
• Sedation
• Decreased libido
• Dark color of urine
• Enlargement of breasts
• Irregular heart rhythm
• Neuroleptic malignant syndrome
• Parkinson’s disease symptoms

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Nitoman with any of the following medications:

• Abilify
• Adenosine
• Alprazolam
• Alprenolol
• Azilect
• Azithromycin
• Benzatropine
• Biperiden
• Bromazepam
• Celebrex
• Chlorpromazine
• Cordarone
• Coreg
• Diazepam
• Doxorubicin
• Elavil
• Isocarboxacid
• Linezolid
• Methylene blue
• Moclobemide
• Phenelzine
• Procarbazine
• Reserpine
• Seleginine
• Symmetrel
• Vfend
• Zolpidem
• Zyrtec

If your doctor orders you to switch Reserpine to Nitoman, 20 days of interval must be observed before you start taking Nitoman

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Nitoman in room temperature (25 °C) in a clean environment away from light and moisture. Keep away from children. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There is no controlled data gathered on human pregnancy. However, as per USA FDA, Tetrabenazine is categorized as Pregnancy Category C which states that no potential and well-controlled studies done in humans, but animal studies have shown adverse effects on the fetus.

The presence of Tetrabenazine in human lactation is still unknown. It is better to consult your doctor first before breastfeeding.

Hence, the use of Nitoman in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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