NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Oralair prescribed?

Doctors prescribe Oralair for allergy immunotherapy to treat symptoms caused by grass pollen allergies. It contains a mix of allergen extracts from five types of grass pollens: sweet vernal, orchard, perennial rye, timothy, and Kentucky bluegrass. This medication is used to reduce symptoms like sneezing, runny or itchy nose, nasal congestion, and itchy or watery eyes in individuals aged 5 to 65 years who are confirmed to be allergic to these grass pollens.

What does it do?

Oralair works by gradually desensitizing the immune system to these allergens, helping to reduce the severity of allergic reactions over time. This medication contains extracts from five types of grass pollens. By introducing small, controlled amounts of these allergens under the tongue, it trains your immune system to tolerate them over time.

How should I take it?

Oralair is taken as a sublingual tablet (placed under the tongue) for allergy immunotherapy. Here are some key reminders for using it:

• Avoid eating or drinking for 5 minutes before and after taking the tablet.
• The first dose should be administered in a healthcare setting under the supervision of a doctor to monitor for any severe allergic reactions.
• For daily use, remove the tablet from the blister pack just before use and place the tablet under your tongue then let it dissolve completely for at least 1 minute before swallowing.
• Start taking Oralair 4 months before the grass pollen season and continue throughout the season.

What if I missed a dose?

If you miss a dose of Oralair, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

What are the special precautions before taking Oralair?

Always inform your doctor about all the medications you are taking, your current and previous medical history.

Before taking Oralair, here are several important precautions to keep in mind:

• Oralair can cause life-threatening allergic reactions, such as anaphylaxis or severe throat swelling. The first dose should always be administered in a healthcare setting under medical supervision.
• This medication is not recommended for individuals with severe, unstable, or uncontrolled asthma
• Do not share Oralair with others, even if they have the same condition, as it could potentially be harmful to them.
• Avoid using Oralair if you have a history of eosinophilic esophagitis, as it may worsen this condition.
• Auto-injectable epinephrine should be made available to patients in case of severe allergic reactions.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Cough
• Itching in the ears
• Swelling, or itching of the mouth or tongue.
• Sore throat
• Throat irritation

Serious side effects may include:
• Dizziness
• Severe allergic reactions, such as difficulty breathing, or throat swelling
• Rapid or irregular heartbeat
• Severe stomach cramps, vomiting, or diarrhea
• Severe flushing or itching of the skin

This is not a complete list of all possible side effects, and others may occur. For more information about side effects, please consult your healthcare provider.

Is it safe to take it with another drug?

Oralair (Five Grass Mixed Pollen Allergen Extract) may interact with other medications, so it's important to take caution before combining it with other drugs. Your allergy specialist might decide against prescribing Oralair if you are currently taking medications that could increase the risk of severe reactions or interfere with managing such reactions. These medications include:

• Beta blockers and alpha-blockers (for high blood pressure)
• Cardiac glycosides (for heart failure or heart rhythm issues)
• Diuretics (for heart conditions or high blood pressure)
• Ergot alkaloids (for migraine headaches)
• Monoamine oxidase inhibitors or tricyclic antidepressants (for depression)
• Thyroid hormones (for low thyroid activity)

It's important to always consult your healthcare provider before combining Oralair with other medications to ensure safety.

How should I store it?

Oralair should be stored in its original packaging at room temperature, ideally between 20°C and 25°C (68°F and 77°F). Keep it away from direct sunlight and out of reach of children and pets.

What action should I take in case of overdose?

If you suspect an overdose of Oralair, it's important to act quickly and seek immediate medical attention. Contact emergency services or go to the nearest hospital. Watch for any unusual reactions, such as severe allergic reaction symptoms, difficulty breathing, or swelling.

Is it safe for pregnant or breastfeeding women?

Oralair (Five Grass Mixed Pollen Allergen Extract) should be used with caution during pregnancy and breastfeeding. It should only be used during pregnancy if clearly needed and prescribed by a healthcare provider. Tell your doctor if you are pregnant or plan to become pregnant before using Oralair.

On the other hand, it is unknown if this medication passes into breast milk, and it should only be used if the potential benefits outweigh the risks to ensure safety.

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