Why is Ortho Tri-cyclen prescribed?

Norgestimate and Ethinyl estradiol (Ortho Tri-cyclen) are oral contraceptives prescribed to prevent pregnancy from occurring. It is also prescribed for the treatment of acne vulgaris (moderate severity) in women 15 years of age and older.

What does it do?

Ortho Tri-cyclen contains two female sex hormones, Norgestimate and Ethinyl estradiol. Norgestimate is classified as a progestin while Ethinyl estradiol is classified as an estrogen. The mechanism of Norgestimate and Ethinyl estradiol to prevent pregnancy is through inhibiting the release of an egg from the ovary and by altering the uterine lining and cervical mucus to prevent sperm from reaching the egg.

How should I take it?

Ortho Tri-cyclen and its generic equivalents are currently available as 0.250mg/0.035mg tablets. Each tablet should be taken as a whole (do not split) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Ortho Tri-cyclen?

Before taking Norgestimate and Ethinyl estradiol, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had high blood pressure, diabetes, high cholesterol levels, heart disease, liver or kidney disease, migraines, seizures, gallbladder problems, thyroid problems, jaundice, or irregular menstrual cycles.

Taking Norgestimate and Ethinyl estradiol can make you susceptible to the formation of blood clots, having a stroke, or heart attacks. Consult your doctor regarding this risk.

For the drug label information of Ortho Tri-cyclen, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Breast tenderness
• Headache
• Nausea
• Nervousness
• Rashes
• Stomach pain
• Vaginal itching or discharge
• Vomiting

Serious side effects include:
• Balance problems
• Chest pain
• Coughing up blood
• Shortness of breath
• Sleep problems
• Slurred speech
• Swollen hands, ankles, or feet
• Vision problems

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Ortho Tri-cyclen with any of the following medications:

• Amprenavir
• Aztreonam
• Bacitracin
• Bexarotene
• Boceprevir
• Bosentan
• Brigatinib
• Carfilzomib
• Ceftaroline
• Dabrafenib
• Dantrolene
• Diflucan
• Dilantin
• Encorafenib
• Eslicarbazepine
• Evista
• Felbamate
• Femara
• Fosamprenavir
• Fosphenytoin
• Griseofulvin
• Hemin
• Lenalidomide
• Mycophenolate mofetil
• Mysoline
• Pexidartinib
• Phenobarbital
• Pomalidomide
• Rifadin
• Tegretol
• Telaprevir
• Thalidomide
• Tranexamic acid
• Trileptal
• Zanaflex

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Ortho Tri-cyclen at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Norgestimate and Ethinyl estradiol to determine drug-associated risks of major maternal defects, miscarriages, and fetal outcomes.

Data indicates the presence of Norgestimate and Ethinyl estradiol in human milk. Consult your doctor first before breastfeeding.

The use of Norgestimate and Ethinyl estradiol in pregnant and breastfeeding women should be carefully evaluated to determine if its potential benefits outweigh the risks.

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