NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Orthovisc prescribed?

Orthovisc is prescribed to treat knee pain caused by osteoarthritis. It contains hyaluronan, a substance similar to the natural fluid in your joints that acts as a lubricant and shock absorber. This treatment is typically used when other arthritis medications such as acetaminophen, exercise, or physical therapy fail to provide adequate relief for arthritis symptoms.

What does it do?

Orthovisc works by mimicking the natural fluid found in your joints, called hyaluronan. This fluid acts as a lubricant and shock absorber, helping your joints move smoothly and reducing friction between bones. In people with osteoarthritis, the natural hyaluronan in the joints may be depleted or of lower quality, leading to pain and stiffness.

When Orthovisc is injected into the knee joint, it restores the cushioning and lubricating properties of the joint fluid. This can help reduce pain, improve mobility, and enhance joint function.

How should I take it?

Orthovisc is administered as an injection (30 mg/2 mL) directly into the knee joint by a healthcare professional. The typical treatment involves weekly injections for 3 to 4 weeks, depending on your doctor's recommendation.

If there is excess fluid in the knee joint, it may be removed before the injection. After receiving the injection, it's important to avoid strenuous activities, such as jogging or heavy lifting, for at least 48 hours to allow the medication to work effectively.

What if I missed a dose?

A healthcare provider typically administers Orthovisc, so missing a dose is uncommon. However, if you miss an injection appointment, it's important to contact your doctor as soon as possible to reschedule. They will guide you on the best course of action to ensure the treatment remains effective.

What are the special precautions before taking Orthovisc?

Inform your doctor about all the medications you are taking, your current and previous medical history. Before taking Orthovisc, here are some important precautions to keep in mind:

• Avoid using Orthovisc if you are allergic to hyaluronan, gram-positive bacterial proteins, or products derived from birds’ such feathers, eggs, or poultry.
• Do not use Orthovisc if you have an infection in your knee, or the skin around the injection site.
• After receiving the injection, avoid strenuous activities like jogging, heavy lifting, or standing for long periods (more than an hour) for at least 48 hours.
• The safety of Orthovisc during pregnancy or breastfeeding has not been established. Consult your doctor before using this medication.
• Orthovisc is not approved for use in individuals under 21 years old.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Back pain
• Joint stiffness
• Headache
• Dizziness
• Temporary pain, swelling, redness, or discomfort at the injection site

Serious side effects may include:
• Difficulty breathing
• Infection around the knee
• Severe joint pain
• Swelling of the face, lips, or throat

This is not a complete list of all possible side effects, and others may occur. For more information about side effects, please consult your healthcare provider.

Is it safe to take it with another drug?

Orthovisc (Sodium Hyaluronate) may interact with other medications, so it's important to take caution before combining it with other drugs. It's crucial to consult your healthcare provider before combining it with other drugs, as the relevance of interactions can vary based on individual circumstances. Your doctor can help assess the risks and determine whether adjustments or monitoring are needed.

How should I store it?

Orthovisc should be stored in its original packaging at room temperature, ideally between 20°C and 25°C (68°F and 77°F). If the packaging is damaged or the product has been exposed to improper conditions, it should not be used.

What action should I take in case of overdose?

An overdose of Orthovisc is unlikely because it is administered by healthcare professionals in a medical setting. However, if you suspect an overdose of Orthovisc (Sodium Hyaluronate), it's important to act quickly and seek immediate medical attention.

Is it safe for pregnant or breastfeeding women?

The safety of Orthovisc for pregnant or breastfeeding women has not been fully established. It is not known whether Orthovisc could harm an unborn baby or if it passes into breast milk. If you are pregnant, planning to become pregnant, or breastfeeding, it’s essential to consult your doctor before using this medication.

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