Why is Plavix prescribed?

Clopidogrel (Plavix) is prescribed in the prevention of blood clot, stroke, peripheral vascular diseases and other circulatory problems like myocardial infarction and unstable angina.

What does it do?

Clopidogrel possess an anti-platelet activity that primarily works by binding irreversibly to its active metabolite causing the inhibition of platelets from sticking together; thus, helping the blood flow smoothly in the body.

How should I take it?

Plavix is available as 75mg tablet that is intended for oral administration as a whole, not to be crushed or chewed, with or without food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember it. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before taking Plavix?

Before taking Clopidogrel, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had bleeding conditions, liver disease, kidney disease, stomach ulcer, haemophilia, brain injury and other clotting disorders.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Plavix, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Abdominal pain
• Diarrhea
• Dizziness
• Fatigue
• Headache
• Urinary tract infection

Serious side effects may include:
• Acute liver failure
• Aplastic anemia
• Black stool
• Bleeding of gums and nose
• Confusion
• Kidney problems
• Purple skin patches
• Slurred speech
• Stomach bleeding
• Tachycardia
• Vomiting of blood
• Yellowish skin and eyes

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Plavix with any of the following medications:

• Aciphex
• Argatroban
• Aspirin
• BIaxin
• Carbatrol
• Cataflam
• Celebrex
• Cimetidine
• Conivaptan
• Coumadin
• Cymbalta
• Diflucan
• Efavirenz
• Eliquis
• Erythromycin
• Esomeprazole
• Isoniazid
• Luvox
• Mobic
• Modafinil
• Morphine
• Nizoral
• Plendil
• Pradaxa
• Prilosec
• Protamine
• Prozac
• Pulmicort
• Rifampin
• Serzone
• Tagamet
• Vfend

If you are using of any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Plavix in room temperature (25 °C) in a clean environment away from light and moisture. Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

If you suspect an overdose, immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Clopidogrel to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. However, the risk to pregnant women and unborn children is association with myocardial infarction and stroke.

The presence of Clopidogrel in human milk is still unknown. Take caution when taking this medication.

Consult your doctor before using this medication in pregnant women or in nursing infants.

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