Why is Plendil prescribed?

Felodipine (Plendil) is prescribed for the treatment of hypertension that may cause atrial fibrillation, angina, myocardial infarction and other heart problems.

What does it do?

Felodipine, a Calcium channel blocker (CCB), is an anti-hypertensive agent that primarily works by inhibiting the reuptake of calcium channels in the arterial smooth muscle cell membrane; thus, reducing the workload, heart rate and relaxes the blood vessels causing smooth blood flow.

How should I take it?

Plendil/Plendil ER and its generic equivalents are currently available as 2.5mg, 5mg and 10mg tablets that should be taken as a whole (do not split) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before using Plendil?

Before taking Felodipine, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had second- or third-degree atrioventricular block, sick sinus syndrome, muscular dystrophy, myasthenia gravis, congestive heart disease, aortic stenosis, low blood pressure, cirrhosis, kidney disease, diabetes and liver disease.

Avoid drinking alcohol as this may cause dizziness or drowsiness which can add to the effects of Felodipine.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Plendil, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Abdominal pain
• Dizziness
• Drowsiness
• Fatigue
• Headache
• Increased urination
• Insomnia
• Muscle cramps
• Rash
• Tingly feeling under the skin
• Weakness

Serious side effects include:
• Dark colored urine
• Dyspnea
• Dysrhythmia
• Gynecomastia
• Jaundice
• Kidney calculus
• Lymphadenopathy
• Myocardial infarction
• Phlebitis
• Swelling of ankles and feet
• Syncope
• Worsening chest pain

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Plendil with any of the following medications:

• Abametapir
• Abilify
• Acebutolol
• Alfuzosin
• Betaxolol
• Biaxin
• Buspirone
• Cilostazol
• Cimetidine
• Claritin
• Colchicine
• Concore
• Conivaptan
• Cordarone
• Cymbalta
• Dantrolene
• Dilantin
• Edoxaban
• Elavil
• Erythromycin
• Flibanserin
• Lanoxin
• Lipitor
• Luvox
• Mevacor
• Nizoral
• Norvasc
• Pimozide
• Plendil
• Pradaxa
• Prozac
• Ranolazine
• Samsca
• Serzone
• Tagamet
• Tenormin
• Valium
• Xanor
• Zocor

If you are using any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Plendil at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Felodipine to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.

Limited data have been established indicating the presence of Felodipine in human milk. Consult your doctor first before breastfeeding.

The use of Felodipine in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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